ENZYME entry: EC 4.1.1.28
| Accepted Name |
|---|
| Aromatic-L-amino-acid decarboxylase.
|
| Alternative Name(s) |
|---|
| 5-hydroxytryptophan decarboxylase. |
| Aromatic amino acid decarboxylase. |
| DOPA decarboxylase. |
| Hydroxytryptophan decarboxylase. |
| L-DOPA decarboxylase. |
| Tryptophan decarboxylase. |
| Reaction catalysed |
|---|
- L-dopa <=> dopamine + CO(2)
- 5-hydroxy-L-tryptophan <=> 5-hydroxytryptamine + CO(2)
|
| Cofactor(s) |
|---|
| Pyridoxal 5'-phosphate.
|
| Comment(s) |
|---|
- Also acts on other aromatic L-amino acids, including L-tryptophan.
- Formerly EC 4.1.1.26 and EC 4.1.1.27.
|
| Cross-references |
|---|
| PROSITE | PDOC00329 |
| BRENDA | 4.1.1.28 |
| EC2PDB | 4.1.1.28 |
| ExplorEnz | 4.1.1.28 |
| PRIAM enzyme-specific profiles | 4.1.1.28 |
| KEGG Ligand Database for Enzyme Nomenclature | 4.1.1.28 |
| IUBMB Enzyme Nomenclature | 4.1.1.28 |
| IntEnz | 4.1.1.28 |
| MEDLINE | Find literature relating to 4.1.1.28 |
| MetaCyc | 4.1.1.28 |
| UniProtKB/Swiss-Prot |
| P27718, DDC_BOVIN; | P34751, DDC_CAEEL; | P17770, DDC_CATRO; |
| P22781, DDC_CAVPO; | O96571, DDC_DROLE; | P05031, DDC_DROME; |
| O96567, DDC_DROSI; | P20711, DDC_HUMAN; | P48861, DDC_MANSE; |
| O88533, DDC_MOUSE; | P80041, DDC_PIG; | P14173, DDC_RAT; |
| P54768, TYDC1_PAPSO; | P54769, TYDC2_PAPSO; | P54770, TYDC3_PAPSO; |
| P54771, TYDC5_PAPSO; |
|
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