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ENZYME entry: EC 4.1.2.45

Accepted Name
Trans-o-hydroxybenzylidenepyruvate hydratase-aldolase.
Alternative Name(s)
2'-hydroxybenzalpyruvate aldolase.
Reaction catalysed
(3E)-4-(2-hydroxyphenyl)-2-oxobut-3-enoate + H(2)O <=> salicylaldehyde + pyruvate
Comment(s)
  • This enzyme is involved in naphthalene degradation.
  • The enzyme catalyzes a retro-aldol reaction in vitro, and it accepts a broad range of aldehydes and 4-substituted 2-oxobut-3-enoates as substrates.
Cross-references
BRENDA4.1.2.45
EC2PDB4.1.2.45
ExplorEnz4.1.2.45
PRIAM enzyme-specific profiles4.1.2.45
KEGG Ligand Database for Enzyme Nomenclature4.1.2.45
IUBMB Enzyme Nomenclature4.1.2.45
IntEnz4.1.2.45
MEDLINEFind literature relating to 4.1.2.45
MetaCyc4.1.2.45
UniProtKB/Swiss-Prot
Q51947, NAHE1_PSEPU;  P0A144, NAHE2_PSEPU;  P0A142, NAHE_PSEAI;  
P0A143, NAHE_PSEU8;  Q9X9Q6, NSAE_SPHXE;  

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All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 4.1.2.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 4.1.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 4.-.-.-