Expasy logo

ENZYME

ENZYME entry: EC 4.1.99.27

Accepted Name
cyclopenase
Reaction catalysed
(-)-cyclopenine <=> H(+) + methyl isocyanate + viridicatin
Comment(s)
  • This fungal enzyme catalyzes a key reaction in the biosynthesis of quinolone compounds, converting the benzodiazepine structure into a quinolone structure.
  • The enzyme is also active with (-)-4'-methoxycyclopenine.
Cross-references
BRENDA4.1.99.27
EC2PDB4.1.99.27
ExplorEnz4.1.99.27
PRIAM enzyme-specific profiles4.1.99.27
KEGG Ligand Database for Enzyme Nomenclature4.1.99.27
IUBMB Enzyme Nomenclature4.1.99.27
IntEnz4.1.99.27
MEDLINEFind literature relating to 4.1.99.27
MetaCyc4.1.99.27
Rhea expert-curated reactions4.1.99.27
UniProtKB/Swiss-Prot
C8VJQ3, ASQI_EMENI

View entry in original ENZYME format
View entry in raw text format (no links)
All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 4.1.99.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 4.1.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 4.-.-.-