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ENZYME

ENZYME entry: EC 4.1.99.29

Accepted Name
5,8-dihydroxy-2-naphthoate synthase
Alternative Name(s)
1,4-dihydroxy-6-naphthoate synthase
Reaction catalysed
cyclic dehypoxanthinylfutalosinate = 1,4-dihydroxy-6-naphthoate + dihydroxyacetone
Comment(s)
The enzyme participates in alternative menaquinone biosynthesis pathways known as the futalosine and modified futalosine pathways, which occurs in some bacterial species including several human pathogens such as Helicobacter pylori, Campylobacter jejuni, and Chlamydia.
Cross-references
BRENDA4.1.99.29
EC2PDB4.1.99.29
ExplorEnz4.1.99.29
PRIAM enzyme-specific profiles4.1.99.29
KEGG Ligand Database for Enzyme Nomenclature4.1.99.29
IUBMB Enzyme Nomenclature4.1.99.29
IntEnz4.1.99.29
MEDLINEFind literature relating to 4.1.99.29
MetaCyc4.1.99.29
Rhea expert-curated reactions4.1.99.29
UniProtKB/Swiss-Prot
Q9KXN1, MQND_STRCOQ5SI12, MQND_THET8

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