ENZYME entry: EC 4.2.1.106

Accepted Name
Bile-acid 7-alpha-dehydratase.
Alternative Name(s)
BA7 alpha dehydratase.
Reaction catalysed
7-alpha,12-alpha-dihydroxy-3-oxochol-4-en-24-oyl-CoA <=> 12-alpha-hydroxy-3-oxochola-4,6-dien-24-oyl-CoA + H(2)O
Comment(s)
This enzyme, characterized from the gut bacterium Clostridium scindens (previously known as Eubacterium sp. strain VPI 12708), participates in the 7-dehydroxylation process associated with bile acid degradation.
Cross-references
BRENDA4.2.1.106
EC2PDB4.2.1.106
ExplorEnz4.2.1.106
PRIAM enzyme-specific profiles4.2.1.106
KEGG Ligand Database for Enzyme Nomenclature4.2.1.106
IUBMB Enzyme Nomenclature4.2.1.106
IntEnz4.2.1.106
MEDLINEFind literature relating to 4.2.1.106
MetaCyc4.2.1.106
UniProtKB/Swiss-Prot
P19412, BAIE_CLOSV

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