ENZYME class: 4.2

Release of 07-Sep-16


Lyases
Carbon-oxygen lyases

All UniProtKB/Swiss-Prot entries corresponding to class 4.2.-.-.

The following ENZYME entries belong to class 4.2.-.-:

4.2.1.1      Carbonate dehydratase
4.2.1.2      Fumarate hydratase
4.2.1.3      Aconitate hydratase
4.2.1.4      Transferred entry: 4.2.1.3
4.2.1.5      Arabinonate dehydratase
4.2.1.6      Galactonate dehydratase
4.2.1.7      Altronate dehydratase
4.2.1.8      Mannonate dehydratase
4.2.1.9      Dihydroxy-acid dehydratase
4.2.1.10     3-dehydroquinate dehydratase
4.2.1.11     Phosphopyruvate hydratase
4.2.1.12     Phosphogluconate dehydratase
4.2.1.13     Transferred entry: 4.3.1.17
4.2.1.14     Transferred entry: 4.3.1.18
4.2.1.15     Transferred entry: 4.4.1.1
4.2.1.16     Transferred entry: 4.3.1.19
4.2.1.17     Enoyl-CoA hydratase
4.2.1.18     Methylglutaconyl-CoA hydratase
4.2.1.19     Imidazoleglycerol-phosphate dehydratase
4.2.1.20     Tryptophan synthase
4.2.1.21     Transferred entry: 4.2.1.22
4.2.1.22     Cystathionine beta-synthase
4.2.1.23     Deleted entry
4.2.1.24     Porphobilinogen synthase
4.2.1.25     L-arabinonate dehydratase
4.2.1.26     Transferred entry: 4.3.1.9
4.2.1.27     Acetylenecarboxylate hydratase
4.2.1.28     Propanediol dehydratase
4.2.1.29     Transferred entry: 4.99.1.6
4.2.1.30     Glycerol dehydratase
4.2.1.31     Maleate hydratase
4.2.1.32     L(+)-tartrate dehydratase
4.2.1.33     3-isopropylmalate dehydratase
4.2.1.34     (S)-2-methylmalate dehydratase
4.2.1.35     (R)-2-methylmalate dehydratase
4.2.1.36     Homoaconitate hydratase
4.2.1.37     Transferred entry: 3.3.2.4
4.2.1.38     Transferred entry: 4.3.1.20
4.2.1.39     Gluconate dehydratase
4.2.1.40     Glucarate dehydratase
4.2.1.41     5-dehydro-4-deoxyglucarate dehydratase
4.2.1.42     Galactarate dehydratase
4.2.1.43     2-dehydro-3-deoxy-L-arabinonate dehydratase
4.2.1.44     Myo-inosose-2 dehydratase
4.2.1.45     CDP-glucose 4,6-dehydratase
4.2.1.46     dTDP-glucose 4,6-dehydratase
4.2.1.47     GDP-mannose 4,6-dehydratase
4.2.1.48     D-glutamate cyclase
4.2.1.49     Urocanate hydratase
4.2.1.50     Pyrazolylalanine synthase
4.2.1.51     Prephenate dehydratase
4.2.1.52     Transferred entry: 4.3.3.7
4.2.1.53     Oleate hydratase
4.2.1.54     Lactoyl-CoA dehydratase
4.2.1.55     3-hydroxybutyryl-CoA dehydratase
4.2.1.56     Itaconyl-CoA hydratase
4.2.1.57     Isohexenylglutaconyl-CoA hydratase
4.2.1.58     Transferred entry: 4.2.1.59
4.2.1.59     3-hydroxyacyl-[acyl-carrier-protein] dehydratase
4.2.1.60     Transferred entry: 4.2.1.59
4.2.1.61     Transferred entry: 4.2.1.59
4.2.1.62     5-alpha-hydroxysteroid dehydratase
4.2.1.63     Transferred entry: 3.3.2.9 and 3.3.2.10
4.2.1.64     Transferred entry: 3.3.2.9 and 3.3.2.10
4.2.1.65     3-cyanoalanine hydratase
4.2.1.66     Cyanide hydratase
4.2.1.67     D-fuconate dehydratase
4.2.1.68     L-fuconate dehydratase
4.2.1.69     Cyanamide hydratase
4.2.1.70     Pseudouridylate synthase
4.2.1.71     Transferred entry: 4.2.1.27
4.2.1.72     Transferred entry: 4.1.1.78
4.2.1.73     Protoaphin-aglucone dehydratase (cyclizing)
4.2.1.74     Long-chain-enoyl-CoA hydratase
4.2.1.75     Uroporphyrinogen-III synthase
4.2.1.76     UDP-glucose 4,6-dehydratase
4.2.1.77     Trans-L-3-hydroxyproline dehydratase
4.2.1.78     (S)-norcoclaurine synthase
4.2.1.79     2-methylcitrate dehydratase
4.2.1.80     2-oxopent-4-enoate hydratase
4.2.1.81     D(-)-tartrate dehydratase
4.2.1.82     Xylonate dehydratase
4.2.1.83     4-oxalmesaconate hydratase
4.2.1.84     Nitrile hydratase
4.2.1.85     Dimethylmaleate hydratase
4.2.1.86     Transferred entry: 4.2.1.98
4.2.1.87     Octopamine dehydratase
4.2.1.88     (R)-synephrine
4.2.1.89     Transferred entry: 2.8.3.21 and 4.2.1.149
4.2.1.90     L-rhamnonate dehydratase
4.2.1.91     Arogenate dehydratase
4.2.1.92     Hydroperoxide dehydratase
4.2.1.93     ATP-dependent NAD(P)H-hydrate dehydratase
4.2.1.94     Scytalone dehydratase
4.2.1.95     Kievitone hydratase
4.2.1.96     4a-hydroxytetrahydrobiopterin dehydratase
4.2.1.97     Phaseollidin hydratase
4.2.1.98     16-alpha-hydroxyprogesterone dehydratase
4.2.1.99     2-methylisocitrate dehydratase
4.2.1.100    Cyclohexa-1,5-dienecarbonyl-CoA hydratase
4.2.1.101    Trans-feruloyl-CoA hydratase
4.2.1.102    Transferred entry: 4.2.1.100
4.2.1.103    Cyclohexyl-isocyanide hydratase
4.2.1.104    Cyanase
4.2.1.105    2-hydroxyisoflavanone dehydratase
4.2.1.106    Bile-acid 7-alpha-dehydratase
4.2.1.107    3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholest-24-enoyl-CoA
             hydratase
4.2.1.108    Ectoine synthase
4.2.1.109    Methylthioribulose 1-phosphate dehydratase
4.2.1.110    Aldos-2-ulose dehydratase
4.2.1.111    1,5-anhydro-D-fructose dehydratase
4.2.1.112    Acetylene hydratase
4.2.1.113    o-succinylbenzoate synthase
4.2.1.114    Methanogen homoaconitase
4.2.1.115    UDP-N-acetylglucosamine 4,6-dehydratase (inverting)
4.2.1.116    3-hydroxypropionyl-CoA dehydratase
4.2.1.117    2-methylcitrate dehydratase (2-methyl-trans-aconitate forming)
4.2.1.118    3-dehydroshikimate dehydratase
4.2.1.119    Enoyl-CoA hydratase 2
4.2.1.120    4-hydroxybutanoyl-CoA dehydratase
4.2.1.121    Colneleate synthase
4.2.1.122    Tryptophan synthase (indole-salvaging)
4.2.1.123    Tetrahymanol synthase
4.2.1.124    Arabidiol synthase
4.2.1.125    Dammarenediol II synthase
4.2.1.126    N-acetylmuramic acid 6-phosphate etherase
4.2.1.127    Linalool dehydratase
4.2.1.128    Lupan-3-beta,20-diol synthase
4.2.1.129    Squalene--hopanol cyclase
4.2.1.130    D-lactate dehydratase
4.2.1.131    Carotenoid 1,2-hydratase
4.2.1.132    2-hydroxyhexa-2,4-dienoate hydratase
4.2.1.133    Copal-8-ol diphosphate hydratase
4.2.1.134    Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase
4.2.1.135    UDP-N-acetylglucosamine 4,6-dehydratase (configuration-retaining)
4.2.1.136    ADP-dependent NAD(P)H-hydrate dehydratase
4.2.1.137    Sporulenol synthase
4.2.1.138    (+)-caryolan-1-ol synthase
4.2.1.139    Medicarpin synthase
4.2.1.140    Gluconate/galactonate dehydratase
4.2.1.141    2-dehydro-3-deoxy-D-arabinonate dehydratase
4.2.1.142    5'-oxoaverantin cyclase
4.2.1.143    Versicolorin B synthase
4.2.1.144    3-amino-5-hydroxybenzoate synthase
4.2.1.145    Capreomycidine synthase
4.2.1.146    L-galactonate dehydratase
4.2.1.147    5,6,7,8-tetrahydromethanopterin hydro-lyase
4.2.1.148    2-methylfumaryl-CoA hydratase
4.2.1.149    Crotonobetainyl-CoA hydratase
4.2.1.150    Short-chain-enoyl-CoA hydratase
4.2.1.151    Chorismate dehydratase
4.2.1.152    Hydroperoxy icosatetraenoate dehydratase
4.2.1.153    3-methylfumaryl-CoA hydratase
4.2.1.154    Tetracenomycin F2 cyclase
4.2.1.155    Methylthioacryloyl-CoA hydratase
4.2.1.156    L-talarate dehydratase
4.2.1.157    (R)-2-hydroxyisocaproyl-CoA dehydratase
4.2.1.158    Galactarate dehydratase (D-threo-forming)
4.2.1.159    dTDP-4-dehydro-6-deoxy-alpha-D-glucopyranose 2,3-dehydratase
4.2.1.160    2,5-diamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one
             isomerase/dehydratase
4.2.1.161    Bisanhydrobacterioruberin hydratase
4.2.1.162    6-deoxy-6-sulfo-D-gluconate dehydratase
4.2.1.163    2-oxo-hept-4-ene-1,7-dioate hydratase
4.2.1.n1     Transferred entry: 4.2.1.126
4.2.1.n2     Transferred entry: 4.2.1.134
4.2.2.1      Hyaluronate lyase
4.2.2.2      Pectate lyase
4.2.2.3      Mannuronate-specific alginate lyase
4.2.2.4      Transferred entry: 4.2.2.20 and 4.2.2.21
4.2.2.5      Chondroitin AC lyase
4.2.2.6      Oligogalacturonide lyase
4.2.2.7      Heparin lyase
4.2.2.8      Heparin-sulfate lyase
4.2.2.9      Pectate disaccharide-lyase
4.2.2.10     Pectin lyase
4.2.2.11     Guluronate-specific alginate lyase
4.2.2.12     Xanthan lyase
4.2.2.13     Exo-(1->4)-alpha-D-glucan lyase
4.2.2.14     Glucuronan lyase
4.2.2.15     Anhydrosialidase
4.2.2.16     Levan fructotransferase (DFA-IV-forming)
4.2.2.17     Inulin fructotransferase (DFA-I-forming)
4.2.2.18     Inulin fructotransferase (DFA-III-forming)
4.2.2.19     Chondroitin B lyase
4.2.2.20     Chondroitin-sulfate-ABC endolyase
4.2.2.21     Chondroitin-sulfate-ABC exolyase
4.2.2.22     Pectate trisaccharide-lyase
4.2.2.23     Rhamnogalacturonan endolyase
4.2.2.24     Rhamnogalacturonan exolyase
4.2.2.25     Gellan lyase
4.2.2.26     Oligo-alginate lyase
4.2.2.n1     Peptidoglycan lytic exotransglycosylase
4.2.2.n2     Peptidoglycan lytic endotransglycosylase
4.2.3.1      Threonine synthase
4.2.3.2      Ethanolamine-phosphate phospho-lyase
4.2.3.3      Methylglyoxal synthase
4.2.3.4      3-dehydroquinate synthase
4.2.3.5      Chorismate synthase
4.2.3.6      Trichodiene synthase
4.2.3.7      Pentalenene synthase
4.2.3.8      Casbene synthase
4.2.3.9      Aristolochene synthase
4.2.3.10     (-)-endo-fenchol synthase
4.2.3.11     Sabinene-hydrate synthase
4.2.3.12     6-pyruvoyltetrahydropterin synthase
4.2.3.13     (+)-delta-cadinene synthase
4.2.3.14     Transferred entry: 4.2.3.119 and 4.2.3.120
4.2.3.15     Myrcene synthase
4.2.3.16     (4S)-limonene synthase
4.2.3.17     Taxadiene synthase
4.2.3.18     Abieta-7,13-diene synthase
4.2.3.19     Ent-kaurene synthase
4.2.3.20     (R)-limonene synthase
4.2.3.21     Vetispiradiene synthase
4.2.3.22     Germacradienol synthase
4.2.3.23     Germacrene-A synthase
4.2.3.24     Amorpha-4,11-diene synthase
4.2.3.25     S-linalool synthase
4.2.3.26     R-linalool synthase
4.2.3.27     Isoprene synthase
4.2.3.28     Ent-cassa-12,15-diene synthase
4.2.3.29     Ent-sandaracopimaradiene synthase
4.2.3.30     Ent-pimara-8(14),15-diene synthase
4.2.3.31     Ent-pimara-9(11),15-diene synthase
4.2.3.32     Levopimaradiene synthase
4.2.3.33     Stemar-13-ene synthase
4.2.3.34     Stemod-13(17)-ene synthase
4.2.3.35     Syn-pimara-7,15-diene synthase
4.2.3.36     Terpentetriene synthase
4.2.3.37     Epi-isozizaene synthase
4.2.3.38     Alpha-bisabolene synthase
4.2.3.39     Epi-cedrol synthase
4.2.3.40     (Z)-gamma-bisabolene synthase
4.2.3.41     Elisabethatriene synthase
4.2.3.42     Aphidicolan-16-beta-ol synthase
4.2.3.43     Fusicocca-2,10(14)-diene synthase
4.2.3.44     Isopimara-7,15-diene synthase
4.2.3.45     Phyllocladan-16-alpha-ol synthase
4.2.3.46     Alpha-farnesene synthase
4.2.3.47     Beta-farnesene synthase
4.2.3.48     (3S,6E)-nerolidol synthase
4.2.3.49     (3R,6E)-nerolidol synthase
4.2.3.50     (+)-alpha-santalene synthase ((2Z,6Z)-farnesyl diphosphate cyclizing)
4.2.3.51     Beta-phellandrene synthase (neryl-diphosphate-cyclizing)
4.2.3.52     (4S)-beta-phellandrene synthase (geranyl-diphosphate-cyclizing)
4.2.3.53     (+)-endo-beta-bergamotene synthase ((2Z,6Z)-farnesyl diphosphate
             cyclizing)
4.2.3.54     (-)-endo-alpha-bergamotene synthase ((2Z,6Z)-farnesyl diphosphate
             cyclizing)
4.2.3.55     (S)-beta-bisabolene synthase
4.2.3.56     Gamma-humulene synthase
4.2.3.57     (-)-beta-caryophyllene synthase
4.2.3.58     Longifolene synthase
4.2.3.59     (E)-gamma-bisabolene synthase
4.2.3.60     Germacrene C synthase
4.2.3.61     5-epiaristolochene synthase
4.2.3.62     (-)-gamma-cadinene synthase ((2Z,6E)-farnesyl diphosphate cyclizing)
4.2.3.63     (+)-cubenene synthase
4.2.3.64     (+)-epicubenol synthase
4.2.3.65     Zingiberene synthase
4.2.3.66     Beta-selinene cyclase
4.2.3.67     Cis-muuroladiene synthase
4.2.3.68     Beta-eudesmol synthase
4.2.3.69     (+)-alpha-barbatene synthase
4.2.3.70     Patchoulol synthase
4.2.3.71     (E,E)-germacrene B synthase
4.2.3.72     Alpha-gurjunene synthase
4.2.3.73     Valencene synthase
4.2.3.74     Presilphiperfolanol synthase
4.2.3.75     (-)-germacrene D synthase
4.2.3.76     (+)-delta-selinene synthase
4.2.3.77     (+)-germacrene D synthase
4.2.3.78     Beta-chamigrene synthase
4.2.3.79     Thujopsene synthase
4.2.3.80     Alpha-longipinene synthase
4.2.3.81     Exo-alpha-bergamotene synthase
4.2.3.82     Alpha-santalene synthase
4.2.3.83     Beta-santalene synthase
4.2.3.84     10-epi-gamma-eudesmol synthase
4.2.3.85     Alpha-eudesmol synthase
4.2.3.86     7-epi-alpha-selinene synthase
4.2.3.87     Alpha-guaiene synthase
4.2.3.88     Viridiflorene synthase
4.2.3.89     (+)-beta-caryophyllene synthase
4.2.3.90     5-epi-alpha-selinene synthase
4.2.3.91     Cubebol synthase
4.2.3.92     (+)-gamma-cadinene synthase
4.2.3.93     Delta-guaiene synthase
4.2.3.94     Gamma-curcumene synthase
4.2.3.95     (-)-alpha-cuprenene synthase
4.2.3.96     Avermitilol synthase
4.2.3.97     (-)-delta-cadinene synthase
4.2.3.98     (+)-T-muurolol synthase
4.2.3.99     Labdatriene synthase
4.2.3.100    Bicyclogermacrene synthase
4.2.3.101    7-epi-sesquithujene synthase
4.2.3.102    Sesquithujene synthase
4.2.3.103    Ent-isokaurene synthase
4.2.3.104    Alpha-humulene synthase
4.2.3.105    Tricyclene synthase
4.2.3.106    (E)-beta-ocimene synthase
4.2.3.107    (+)-car-3-ene synthase
4.2.3.108    1,8-cineole synthase
4.2.3.109    (-)-sabinene synthase
4.2.3.110    (+)-sabinene synthase
4.2.3.111    (-)-alpha-terpineol synthase
4.2.3.112    (+)-alpha-terpineol synthase
4.2.3.113    Terpinolene synthase
4.2.3.114    Gamma-terpinene synthase
4.2.3.115    Alpha-terpinene synthase
4.2.3.116    (+)-camphene synthase
4.2.3.117    (-)-camphene synthase
4.2.3.118    2-methylisoborneol synthase
4.2.3.119    (-)-alpha-pinene synthase
4.2.3.120    (-)-beta-pinene synthase
4.2.3.121    (+)-alpha-pinene synthase
4.2.3.122    (+)-beta-pinene synthase
4.2.3.123    Beta-sesquiphellandrene synthase
4.2.3.124    2-deoxy-scyllo-inosose synthase
4.2.3.125    Alpha-muurolene synthase
4.2.3.126    Gamma-muurolene synthase
4.2.3.127    Beta-copaene synthase
4.2.3.128    Beta-cubebene synthase
4.2.3.129    (+)-sativene synthase
4.2.3.130    Tetraprenyl-beta-curcumene synthase
4.2.3.131    Miltiradiene synthase
4.2.3.132    Neoabietadiene synthase
4.2.3.133    Alpha-copaene synthase
4.2.3.134    5-phosphonooxy-L-lysine phospho-lyase
4.2.3.135    Delta(6)-protoilludene synthase
4.2.3.136    Alpha-isocomene synthase
4.2.3.137    (E)-2-epi-beta-caryophyllene synthase
4.2.3.138    (+)-epi-alpha-bisabolol synthase
4.2.3.139    Valerena-4,7(11)-diene synthase
4.2.3.140    Cis-abienol synthase
4.2.3.141    Sclareol synthase
4.2.3.142    7-epizingiberene synthase ((2Z,6Z)-farnesyl diphosphate cyclizing)
4.2.3.143    Kunzeaol synthase
4.2.3.144    Geranyllinalool synthase
4.2.3.145    Ophiobolin F synthase
4.2.3.146    Cyclooctat-9-en-7-ol synthase
4.2.3.147    Pimaradiene synthase
4.2.3.148    Cembrene C synthase
4.2.3.149    Nephthenol synthase
4.2.3.150    Cembrene A synthase
4.2.3.151    Pentamethylcyclopentadecatrienol synthase
4.2.3.152    2-epi-5-epi-valiolone synthase
4.2.3.153    (5-formylfuran-3-yl)methyl phosphate synthase
4.2.3.n1     Transferred entry: 4.2.3.38
4.2.3.n2     Delta-selinene synthase
4.2.3.n3     Transferred entry: 4.2.3.56
4.2.3.n4     Transferred entry: 4.2.3.117
4.2.3.n5     Transferred entry: 4.2.3.52
4.2.3.n6     Transferred entry: 4.2.3.113
4.2.3.n7     Transferred entry: 4.2.3.119
4.2.3.n8     Transferred entry: 4.2.3.103
4.2.3.n9     Transferred entry: 4.2.3.44
4.2.3.n10    Transferred entry: 4.2.3.62
4.2.3.n11    Selinene synthase
4.2.3.n12    Transferred entry: 4.2.3.65
4.2.3.n13    Transferred entry: 4.2.3.75
4.2.3.n14    Transferred entry: 4.2.3.118
4.2.99.1     Transferred entry: 4.2.2.1
4.2.99.2     Transferred entry: 4.2.3.1
4.2.99.3     Transferred entry: 4.2.2.2
4.2.99.4     Transferred entry: 4.2.2.3
4.2.99.5     Deleted entry
4.2.99.6     Transferred entry: 4.2.2.5, 4.2.2.20 and 4.2.2.21
4.2.99.7     Transferred entry: 4.2.3.2
4.2.99.8     Transferred entry: 2.5.1.47
4.2.99.9     Transferred entry: 2.5.1.48
4.2.99.10    Transferred entry: 2.5.1.49
4.2.99.11    Transferred entry: 4.2.3.3
4.2.99.12    Carboxymethyloxysuccinate lyase
4.2.99.13    Transferred entry: 2.5.1.50
4.2.99.14    Transferred entry: 2.5.1.51
4.2.99.15    Transferred entry: 2.5.1.52
4.2.99.16    Transferred entry: 2.5.1.53
4.2.99.17    Transferred entry: 2.5.1.51
4.2.99.18    DNA-(apurinic or apyrimidinic site) lyase
4.2.99.19    Transferred entry: 4.4.1.23
4.2.99.20    2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase
4.2.99.21    Isochorismate lyase
4.2.99.22    Tuliposide A-converting enzyme
4.2.99.23    Tuliposide B-converting enzyme
4.2.99.n1    Transferred entry: 4.2.99.20