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ENZYME entry: EC 4.2.2.2

Accepted Name
Pectate lyase.
Alternative Name(s)
Alpha-1,4-D-endopolygalacturonic acid lyase.
Endo-alpha-1,4-polygalacturonic acid lyase.
Endogalacturonate transeliminase.
Endopectin methyltranseliminase.
Pectate transeliminase.
Pectic acid lyase.
Pectic acid transeliminase.
Pectic lyase.
Pectin trans-eliminase.
PGA lyase.
Polygalacturonate lyase.
Polygalacturonic acid lyase.
Polygalacturonic acid trans-eliminase.
Polygalacturonic transeliminase.
PPase-N.
Reaction catalysed
Eliminative cleavage of (1->4)-alpha-D-galacturonan to give oligosaccharides with 4-deoxy-alpha-D-galact-4-enuronosyl groups at their non-reducing ends
Comment(s)
  • Favors pectate, the anion, over pectin, the methyl ester (which is the preferred substrate of EC 4.2.2.10).
  • Formerly EC 4.2.99.3.
Cross-references
BRENDA4.2.2.2
EC2PDB4.2.2.2
ExplorEnz4.2.2.2
PRIAM enzyme-specific profiles4.2.2.2
KEGG Ligand Database for Enzyme Nomenclature4.2.2.2
IUBMB Enzyme Nomenclature4.2.2.2
IntEnz4.2.2.2
MEDLINEFind literature relating to 4.2.2.2
MetaCyc4.2.2.2
UniProtKB/Swiss-Prot
Q9LJ42, PLY10_ARATH;  Q9LTZ0, PLY11_ARATH;  Q9SCP2, PLY12_ARATH;  
Q93Z04, PLY13_ARATH;  Q9SVQ6, PLY14_ARATH;  Q944R1, PLY15_ARATH;  
O65456, PLY16_ARATH;  O65457, PLY17_ARATH;  Q9C5M8, PLY18_ARATH;  
P24396, PLY18_SOLLC;  Q9LFP5, PLY19_ARATH;  P27760, PLY1_AMBAR;  
Q940Q1, PLY1_ARATH;  Q96385, PLY1_CHAOB;  P18632, PLY1_CRYJA;  
Q9SCG9, PLY1_HESAR;  P81294, PLY1_JUNAS;  Q9LLT1, PLY1_JUNVI;  
Q6CZT4, PLY1_PECAS;  P0C1C0, PLY1_PECCA;  Q93WF1, PLY20_ARATH;  
Q9FM66, PLY21_ARATH;  Q93Z25, PLY22_ARATH;  P27761, PLY2_AMBAR;  
O65388, PLY2_ARATH;  Q6CZT3, PLY2_PECAS;  P0C1C1, PLY2_PECCA;  
P28744, PLY3_AMBAR;  Q9M9S2, PLY3_ARATH;  Q6CZT2, PLY3_PECAS;  
P0C1C2, PLY3_PECCA;  P0C1C3, PLY3_PECCC;  P27762, PLY4_AMBAR;  
Q9C8G4, PLY4_ARATH;  P15721, PLY56_SOLLC;  P15722, PLY59_SOLLC;  
P27759, PLY5_AMBAR;  Q9FXD8, PLY5_ARATH;  O64510, PLY6_ARATH;  
Q9SRH4, PLY7_ARATH;  Q9M8Z8, PLY8_ARATH;  Q9LRM5, PLY9_ARATH;  
B0XT32, PLYA_ASPFC;  B8NE46, PLYA_ASPFN;  Q4WIT0, PLYA_ASPFU;  
A2QV36, PLYA_ASPNC;  Q9C2Z0, PLYA_ASPNG;  Q2U8R6, PLYA_ASPOR;  
P0C1A2, PLYA_DICCH;  P0C1A3, PLYA_DICD3;  Q5AVN4, PLYA_EMENI;  
A1CYB8, PLYA_NEOFI;  D3JTC1, PLYA_PAEAM;  Q9X6Z2, PLYA_PAEBA;  
B8NBC2, PLYB_ASPFN;  Q2TZY0, PLYB_ASPOR;  Q0CBV0, PLYB_ASPTN;  
O59939, PLYB_COLGL;  P04959, PLYB_DICCH;  Q00645, PLYB_EMENI;  
D3JTC2, PLYB_PAEAM;  B0XMA2, PLYC_ASPFC;  B8NQQ7, PLYC_ASPFN;  
Q4WL88, PLYC_ASPFU;  Q2UB83, PLYC_ASPOR;  Q0CLG7, PLYC_ASPTN;  
Q65EF5, PLYC_BACLD;  O34310, PLYC_BACSU;  P11073, PLYC_DICCH;  
Q5B297, PLYC_EMENI;  A1DPF0, PLYC_NEOFI;  B0YB89, PLYD_ASPFC;  
Q4WGV9, PLYD_ASPFU;  Q0CJ49, PLYD_ASPTN;  P18209, PLYD_DICCH;  
Q5BA88, PLYD_EMENI;  A1DCY5, PLYD_NEOFI;  P04960, PLYE1_DICCH;  
P0C1A4, PLYE2_DICCH;  A1C4B8, PLYE_ASPCL;  B0Y9M8, PLYE_ASPFC;  
B8NX10, PLYE_ASPFN;  Q4WC29, PLYE_ASPFU;  Q2TW49, PLYE_ASPOR;  
P0C1A5, PLYE_DICD3;  Q5B7Z3, PLYE_EMENI;  A1DBJ7, PLYE_NEOFI;  
B0Y953, PLYF_ASPFC;  B8NJZ7, PLYF_ASPFN;  Q4WKV8, PLYF_ASPFU;  
Q0CCF8, PLYF_ASPTN;  Q5B024, PLYF_EMENI;  A1D5E3, PLYF_NEOFI;  
Q0CJ20, PLYG_ASPTN;  Q5AY82, PLYG_EMENI;  Q5ATC7, PLYH_EMENI;  
P0C1A6, PLYL_DICCH;  P0C1A7, PLYL_DICD3;  P14005, PLYP_PECCC;  
P11278, PLYP_YERPS;  P16530, PLYX_PECCA;  P39116, PLY_BACSU;  
P40973, PLY_LILLO;  P72242, PLY_PSEAV;  Q59671, PLY_PSEFL;  
Q51915, PLY_PSEMA;  Q60140, PLY_PSEVI;  P40972, PLY_TOBAC;  
Q56806, PLY_XANCM;  O24554, PLY_ZINVI;  

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All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 4.2.2.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 4.2.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 4.-.-.-