ENZYME entry: EC 4.2.3.32

Accepted Name
Levopimaradiene synthase.
Reaction catalysed
(+)-copalyl diphosphate <=> abieta-8(14),12-diene + diphosphate
Comment(s)
  • In Ginkgo, the enzyme catalyzes the initial cyclization step in the biosynthesis of ginkgolides, a structurally unique family of diterpenoids that are highly specific platelet-activating-factor receptor antagonists.
  • Levopimaradiene is widely distributed in higher plants.
  • In some species the enzyme also forms abietadiene, palustradiene, and neoabietadiene.
Cross-references
BRENDA4.2.3.32
EC2PDB4.2.3.32
ExplorEnz4.2.3.32
PRIAM enzyme-specific profiles4.2.3.32
KEGG Ligand Database for Enzyme Nomenclature4.2.3.32
IUBMB Enzyme Nomenclature4.2.3.32
IntEnz4.2.3.32
MEDLINEFind literature relating to 4.2.3.32
MetaCyc4.2.3.32
UniProtKB/Swiss-Prot
H8ZM70, LAS_ABIBA;  Q947C4, TPSD1_GINBI;  Q675L4, TPSD1_PICAB;  
Q50EK2, TPSD1_PINTA;  

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All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 4.2.3.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 4.2.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 4.-.-.-