ENZYME entry: EC 4.2.3.7

Accepted Name
Pentalenene synthase.
Alternative Name(s)
Pentalenene synthetase.
Reaction catalysed
(2E,6E)-farnesyl diphosphate <=> pentalenene + diphosphate
Comment(s)
  • Isolated from Streptomyces avermitilis.
  • The enzyme is involved in the biosynthesis of pentalenolactone and related antibiotics.
  • The 9si hydrogen of farnesyl diphosphate undergoes a 1,2-hydride shift where it becomes the 1-alpha hydrogen of pentalenene.
  • Formerly EC 4.6.1.5.
Cross-references
BRENDA4.2.3.7
EC2PDB4.2.3.7
ExplorEnz4.2.3.7
PRIAM enzyme-specific profiles4.2.3.7
KEGG Ligand Database for Enzyme Nomenclature4.2.3.7
IUBMB Enzyme Nomenclature4.2.3.7
IntEnz4.2.3.7
MEDLINEFind literature relating to 4.2.3.7
MetaCyc4.2.3.7
UniProtKB/Swiss-Prot
Q55012, PENA_STREX;  E3VWJ0, PNTA_STRAE;  Q82IY4, PTLA_STRAW;  

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 4.2.3.-
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