To improve security and privacy, we are moving our web pages and services from HTTP to HTTPS.
To give users of web services time to transition to HTTPS, we will support separate HTTP and HTTPS services until the end of 2017.
From January 2018 most HTTP traffic will be automatically redirected to HTTPS. [more...]
View this page in https

ENZYME entry: EC 5.4.2.4

Accepted Name
Bisphosphoglycerate mutase.
Alternative Name(s)
2,3-bisphosphoglycerate mutase.
2,3-bisphosphoglycerate synthase.
2,3-diphosphoglycerate mutase.
Bisphosphoglycerate synthase.
BPGM.
Diphosphoglycerate mutase.
Diphosphoglyceromutase.
Glycerate phosphomutase.
Reaction catalysed
3-phospho-D-glyceroyl phosphate <=> 2,3-bisphospho-D-glycerate
Comment(s)
  • In the direction shown, the enzyme is phosphorylated by 3-phosphoglyceroyl phosphate to give phosphoenzyme and 3-phosphoglycerate.
  • The latter is rephosphorylated by the enzyme to yield 2,3- diphosphoglycerate, but this reaction is slowed down by dissociation of 3-phosphoglycerate from the enzyme, which is therefore more active in the presence of added 3-phosphoglycerate.
  • Also catalyzes, slowly, the reaction of EC 5.4.2.12.
  • Formerly EC 2.7.5.4.
Cross-references
PROSITEPDOC00158
BRENDA5.4.2.4
EC2PDB5.4.2.4
ExplorEnz5.4.2.4
PRIAM enzyme-specific profiles5.4.2.4
KEGG Ligand Database for Enzyme Nomenclature5.4.2.4
IUBMB Enzyme Nomenclature5.4.2.4
IntEnz5.4.2.4
MEDLINEFind literature relating to 5.4.2.4
MetaCyc5.4.2.4
UniProtKB/Swiss-Prot
Q3SZ62, PGAM1_BOVIN;  Q5ZLN1, PGAM1_CHICK;  P18669, PGAM1_HUMAN;  
Q9DBJ1, PGAM1_MOUSE;  Q5RFB8, PGAM1_PONAB;  P25113, PGAM1_RAT;  
Q32KV0, PGAM2_BOVIN;  P15259, PGAM2_HUMAN;  O70250, PGAM2_MOUSE;  
P16290, PGAM2_RAT;  Q8N0Y7, PGAM4_HUMAN;  Q8MKE8, PGAM4_PANTR;  
Q54NE6, PGAM_DICDI;  Q3T014, PMGE_BOVIN;  P07738, PMGE_HUMAN;  
Q4R6L7, PMGE_MACFA;  P15327, PMGE_MOUSE;  P07952, PMGE_RABIT;  

View entry in original ENZYME format
View entry in raw text format (no links)

All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 5.4.2.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 5.4.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 5.-.-.-