ENZYME entry: EC 6.3.2.11
| Accepted Name |
|---|
| Carnosine synthase.
|
| Alternative Name(s) |
|---|
| Carnosine synthetase. |
| Reaction catalysed |
|---|
| ATP + L-histidine + beta-alanine <=> ADP + phosphate + carnosine |
| Comment(s) |
|---|
- This enzyme was thought to form AMP, but studies with highly purified
enzyme proved that it forms ADP.
- Carnosine is a dipeptide that is present at high concentrations in
skeletal muscle and the olfactory bulb of vertebrates.
- It is also found in the skeletal muscle of some invertebrates.
- The enzyme can also catalyze the formation of homocarnosine from
4-aminobutyrate and L-histidine, with much lower activity.
|
| Cross-references |
|---|
| BRENDA | 6.3.2.11 |
| EC2PDB | 6.3.2.11 |
| ExplorEnz | 6.3.2.11 |
| PRIAM enzyme-specific profiles | 6.3.2.11 |
| KEGG Ligand Database for Enzyme Nomenclature | 6.3.2.11 |
| IUBMB Enzyme Nomenclature | 6.3.2.11 |
| IntEnz | 6.3.2.11 |
| MEDLINE | Find literature relating to 6.3.2.11 |
| MetaCyc | 6.3.2.11 |
| UniProtKB/Swiss-Prot |
|
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