ENZYME entry: EC 6.3.2.27
| Accepted Name |
|---|
| Aerobactin synthase.
|
| Reaction catalysed |
|---|
| 4 ATP + citrate + 2 N(6)-acetyl-N(6)-hydroxy-L-lysine + 2 H(2)O <=> 4 ADP + 4 phosphate + aerobactin |
| Cofactor(s) |
|---|
| Magnesium.
|
| Comment(s) |
|---|
- Aerobactin is one of a group of high-affinity iron chelators known as
siderophores and is produced under conditions of iron deprivation.
- It is a dihydroxamate comprising two molecules of N(6)-acetyl-N(6)-
hydroxylysine and one molecule of citric acid.
- This is the last of the three enzymes involved in its synthesis,
the others being EC 1.14.13.59 and EC 2.3.1.102.
|
| Cross-references |
|---|
| BRENDA | 6.3.2.27 |
| EC2PDB | 6.3.2.27 |
| ExplorEnz | 6.3.2.27 |
| PRIAM enzyme-specific profiles | 6.3.2.27 |
| KEGG Ligand Database for Enzyme Nomenclature | 6.3.2.27 |
| IUBMB Enzyme Nomenclature | 6.3.2.27 |
| IntEnz | 6.3.2.27 |
| MEDLINE | Find literature relating to 6.3.2.27 |
| MetaCyc | 6.3.2.27 |
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ENZYME /
UniProtKB/Swiss-Prot entries corresponding to 6.3.2.-
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ENZYME /
UniProtKB/Swiss-Prot entries corresponding to 6.3.-.-
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ENZYME /
UniProtKB/Swiss-Prot entries corresponding to 6.-.-.-