ENZYME entry: EC 1.1.1.110
Accepted Name |
Aromatic 2-oxoacid reductase.
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Alternative Name(s) |
(R)-4-hydroxyphenyllactate dehydrogenase. |
(R)-aromatic lactate dehydrogenase. |
Indole-3-lactate dehydrogenase. |
Indolelactate dehydrogenase. |
Reaction catalysed |
- (R)-3-(phenyl)lactate + NAD(+) <=> 3-phenyl-2-oxopropanoate + NADH
- (R)-3-(4-hydroxyphenyl)lactate + NAD(+) <=> 3-(4-hydroxyphenyl)pyruvate + NADH
- (Indol-3-yl)lactate + NAD(+) <=> (indol-3-yl)pyruvate + NADH
|
Comment(s) |
- The enzymes from anaerobic bacteria such as Clostridium sporogenes
participate in the fermentation pathways of L-phenylalanine,
L-tyrosine and L-tryptophan.
- The enzyme from the yeast Candida maltosa has similar activity, but,
unlike the bacterial enzyme, requires Mn(2+) and can also use NADPH
with lower activity.
- Formerly EC 1.1.1.222.
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Cross-references |
BRENDA | 1.1.1.110 |
EC2PDB | 1.1.1.110 |
ExplorEnz | 1.1.1.110 |
PRIAM enzyme-specific profiles | 1.1.1.110 |
KEGG Ligand Database for Enzyme Nomenclature | 1.1.1.110 |
IUBMB Enzyme Nomenclature | 1.1.1.110 |
IntEnz | 1.1.1.110 |
MEDLINE | Find literature relating to 1.1.1.110 |
MetaCyc | 1.1.1.110 |
Rhea expert-curated reactions | 1.1.1.110 |
UniProtKB/Swiss-Prot |
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