Expasy logo

ENZYME

ENZYME entry: EC 1.1.1.209

PURL: https://purl.expasy.org/enzyme/EC/1.1.1.209
Accepted Name
3(or 17)alpha-hydroxysteroid dehydrogenase
Reaction catalysed
  • androsterone + NADP(+) = 5alpha-androstan-3,17-dione + NADPH + H(+)
  • androsterone + NAD(+) = 5alpha-androstan-3,17-dione + NADH + H(+)
Comment(s)
Acts on the 3alpha-hydroxy group of androgens of the 5alpha- androstane series; and also, more slowly, on the 17alpha-hydroxyl group of both androgenic and estrogenic substrates (cf. EC 1.1.1.51).
Cross-references
BRENDA1.1.1.209
EC2PDB1.1.1.209
ExplorEnz1.1.1.209
KEGG Ligand Database for Enzyme Nomenclature1.1.1.209
IUBMB Enzyme Nomenclature1.1.1.209
MEDLINEFind literature relating to 1.1.1.209
MetaCyc1.1.1.209
Rhea expert-curated reactions1.1.1.209
UniProtKB/Swiss-Prot
Q04828, AK1C1_HUMANQ95JH7, AK1C1_MACFAQ95JH6, AK1C1_MACFU
Q5REQ0, AK1C1_PONABP52895, AK1C2_HUMANP52898, AK1C4_BOVIN
P17516, AK1C4_HUMANQ95JH5, AK1C4_MACFAQ95JH4, AK1C4_MACFU
Q91WR5, AK1CL_MOUSEQ6AYQ2, AK1CL_RATQ8HYR6, DHRS9_BOVIN
Q9BPW9, DHRS9_HUMANQ58NB6, DHRS9_MOUSEQ8VD48, DHRS9_RAT
Q3T001, H17B6_BOVINO14756, H17B6_HUMANQ9R092, H17B6_MOUSE
O54753, H17B6_RATO75452, RDH16_HUMANO54909, RDH16_MOUSE
P50170, RDH16_RATQ27979, RDH5_BOVINQ92781, RDH5_HUMAN
O55240, RDH5_MOUSE

View entry in original ENZYME format
View entry in raw text format (no links)
All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.1.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.1.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.-.-.-