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ENZYME entry: EC 1.1.1.209

Accepted Name
3(or 17)-alpha-hydroxysteroid dehydrogenase.
Reaction catalysed
Androsterone + NAD(P)(+) <=> 5-alpha-androstane-3,17-dione + NAD(P)H
Comment(s)
Acts on the 3-alpha-hydroxy group of androgens of the 5-alpha- androstane series; and also, more slowly, on the 17-alpha-hydroxyl group of both androgenic and estrogenic substrates (cf. EC 1.1.1.51).
Cross-references
BRENDA1.1.1.209
EC2PDB1.1.1.209
ExplorEnz1.1.1.209
PRIAM enzyme-specific profiles1.1.1.209
KEGG Ligand Database for Enzyme Nomenclature1.1.1.209
IUBMB Enzyme Nomenclature1.1.1.209
IntEnz1.1.1.209
MEDLINEFind literature relating to 1.1.1.209
MetaCyc1.1.1.209
UniProtKB/Swiss-Prot
Q91WR5, AK1CL_MOUSE;  Q6AYQ2, AK1CL_RAT;  Q8HYR6, DHRS9_BOVIN;  
Q9BPW9, DHRS9_HUMAN;  Q58NB6, DHRS9_MOUSE;  Q8VD48, DHRS9_RAT;  
O75452, RDH16_HUMAN;  O54909, RDH16_MOUSE;  P50170, RDH16_RAT;  
Q27979, RDH5_BOVIN;  Q92781, RDH5_HUMAN;  O55240, RDH5_MOUSE;  

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