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ENZYME entry: EC 1.1.1.51

Accepted Name
3(or 17)beta-hydroxysteroid dehydrogenase.
Reaction catalysed
  • NAD(+) + testosterone <=> androst-4-ene-3,17-dione + H(+) + NADH
  • NADP(+) + testosterone <=> androst-4-ene-3,17-dione + H(+) + NADPH
Comment(s)
Also acts on other 3beta- or 17beta-hydroxysteroids (cf. EC 1.1.1.209).
Cross-references
BRENDA1.1.1.51
EC2PDB1.1.1.51
ExplorEnz1.1.1.51
PRIAM enzyme-specific profiles1.1.1.51
KEGG Ligand Database for Enzyme Nomenclature1.1.1.51
IUBMB Enzyme Nomenclature1.1.1.51
IntEnz1.1.1.51
MEDLINEFind literature relating to 1.1.1.51
MetaCyc1.1.1.51
Rhea expert-curated reactions1.1.1.51
UniProtKB/Swiss-Prot
P19871, 3BHD_COMTE;  Q04828, AK1C1_HUMAN;  Q95JH7, AK1C1_MACFA;  
Q95JH6, AK1C1_MACFU;  Q5REQ0, AK1C1_PONAB;  P17516, AK1C4_HUMAN;  
Q95JH5, AK1C4_MACFA;  Q95JH4, AK1C4_MACFU;  P14061, DHB1_HUMAN;  
P51656, DHB1_MOUSE;  O18404, HCD2_DROME;  

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