A new class EC 7, Translocases, has been added to the EC list. It will be part of ENZYME from release 2018_10. Read more about EC 7 here.
ENZYME entry: EC 1.1.1.218
| Accepted Name |
|---|
| Morphine 6-dehydrogenase.
|
| Alternative Name(s) |
|---|
| Naloxone reductase. |
| Reaction catalysed |
|---|
| Morphine + NAD(P)(+) <=> morphinone + NAD(P)H |
| Comment(s) |
|---|
- Also acts on some other alkaloids, including codeine, normorphine and
ethylmorphine, but only very slowly on 7,8-saturated derivatives such
as dihydromorphine and dihydrocodeine.
- In the reverse direction, also reduces naloxone to the 6-alpha-
hydroxy analog.
- Activated by 2-mercaptoethanol.
|
| Cross-references |
|---|
| PROSITE | PDOC00061 |
| BRENDA | 1.1.1.218 |
| EC2PDB | 1.1.1.218 |
| ExplorEnz | 1.1.1.218 |
| PRIAM enzyme-specific profiles | 1.1.1.218 |
| KEGG Ligand Database for Enzyme Nomenclature | 1.1.1.218 |
| IUBMB Enzyme Nomenclature | 1.1.1.218 |
| IntEnz | 1.1.1.218 |
| MEDLINE | Find literature relating to 1.1.1.218 |
| MetaCyc | 1.1.1.218 |
| UniProtKB/Swiss-Prot |
|
View entry in original ENZYME format
View entry in raw text format (no links)
All UniProtKB/Swiss-Prot
entries referenced
in this entry, with possibility to download in different formats, align etc.
All
ENZYME /
UniProtKB/Swiss-Prot entries corresponding to 1.1.1.-
All
ENZYME /
UniProtKB/Swiss-Prot entries corresponding to 1.1.-.-
All
ENZYME /
UniProtKB/Swiss-Prot entries corresponding to 1.-.-.-