ENZYME entry: EC 1.1.1.239
Accepted Name |
3-alpha-(17-beta)-hydroxysteroid dehydrogenase (NAD(+)).
|
Alternative Name(s) |
17-beta-HSD. |
17-ketoreductase. |
Reaction catalysed |
Testosterone + NAD(+) <=> androstenedione + NADH |
Comment(s) |
- Also acts on other 17-beta-hydroxysteroids, on the 3-alpha-hydroxy
group of pregnanes and bile acids.
- Different from EC 1.1.1.50 or EC 1.1.1.213.
- Formerly EC 1.1.1.63.
|
Cross-references |
BRENDA | 1.1.1.239 |
EC2PDB | 1.1.1.239 |
ExplorEnz | 1.1.1.239 |
PRIAM enzyme-specific profiles | 1.1.1.239 |
KEGG Ligand Database for Enzyme Nomenclature | 1.1.1.239 |
IUBMB Enzyme Nomenclature | 1.1.1.239 |
IntEnz | 1.1.1.239 |
MEDLINE | Find literature relating to 1.1.1.239 |
MetaCyc | 1.1.1.239 |
Rhea expert-curated reactions | 1.1.1.239 |
UniProtKB/Swiss-Prot |
P42330, AK1C3_HUMAN; | Q5R7C9, AK1C3_PONAB; | P37059, DHB2_HUMAN; |
P51658, DHB2_MOUSE; | Q62730, DHB2_RAT; | Q9GME3, DHB8_CALJA; |
Q5TJF5, DHB8_CANLF; | Q92506, DHB8_HUMAN; | P50171, DHB8_MOUSE; |
Q9XT00, DHB8_PIG; | Q6MGB5, DHB8_RAT; | Q3T001, H17B6_BOVIN; |
O14756, H17B6_HUMAN; | Q9R092, H17B6_MOUSE; | O54753, H17B6_RAT; |
O02691, HCD2_BOVIN; | Q99714, HCD2_HUMAN; | O08756, HCD2_MOUSE; |
O70351, HCD2_RAT; |
|
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ENZYME /
UniProtKB/Swiss-Prot entries corresponding to 1.1.1.-
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