A new class EC 7, Translocases, has been added to the EC list. It will be part of ENZYME from release 2018_10. Read more about EC 7 here.
ENZYME entry: EC 1.1.1.298
| Accepted Name |
|---|
| 3-hydroxypropionate dehydrogenase (NADP(+)).
|
| Alternative Name(s) |
|---|
| 3-hydroxypropanoate dehydrogenase (NADP(+)). |
| Reaction catalysed |
|---|
| 3-hydroxypropanoate + NADP(+) <=> 3-oxopropanoate + NADPH |
| Comment(s) |
|---|
- Catalyzes the reduction of 3-oxopropanoate to 3-hydroxypropanoate,
a key step in the 3-hydroxypropanoate and the
3-hydroxypropanoate/4-hydroxybutyrate cycles, autotrophic CO(2)
fixation pathways found in some green non-sulfur phototrophic
bacteria and archaea, respectively.
- The enzyme from Chloroflexus aurantiacus is bifunctional, and also
catalyzes the upstream reaction in the pathway, EC 1.2.1.75.
- Different from EC 1.1.1.59 by cofactor preference.
|
| Cross-references |
|---|
| BRENDA | 1.1.1.298 |
| EC2PDB | 1.1.1.298 |
| ExplorEnz | 1.1.1.298 |
| PRIAM enzyme-specific profiles | 1.1.1.298 |
| KEGG Ligand Database for Enzyme Nomenclature | 1.1.1.298 |
| IUBMB Enzyme Nomenclature | 1.1.1.298 |
| IntEnz | 1.1.1.298 |
| MEDLINE | Find literature relating to 1.1.1.298 |
| MetaCyc | 1.1.1.298 |
| UniProtKB/Swiss-Prot |
| A7MFX7, RUTE_CROS8; | A7ZKB3, RUTE_ECO24; | B7UNZ1, RUTE_ECO27; |
| B7MIF5, RUTE_ECO45; | B7LFB8, RUTE_ECO55; | Q8XAU9, RUTE_ECO57; |
| B5YU50, RUTE_ECO5E; | B7NLB8, RUTE_ECO7I; | B7MTF1, RUTE_ECO81; |
| B7M8Z3, RUTE_ECO8A; | C4ZQD6, RUTE_ECOBW; | B1X9C9, RUTE_ECODH; |
| A7ZYW3, RUTE_ECOHS; | A1A9R3, RUTE_ECOK1; | Q0TJ59, RUTE_ECOL5; |
| Q8FJ44, RUTE_ECOL6; | B1IV89, RUTE_ECOLC; | P75894, RUTE_ECOLI; |
| B7N3G4, RUTE_ECOLU; | B6I984, RUTE_ECOSE; | B1LIZ7, RUTE_ECOSM; |
| Q1RDK9, RUTE_ECOUT; | A4W921, RUTE_ENT38; | B5XXN4, RUTE_KLEP3; |
| A6T798, RUTE_KLEP7; | Q32HQ3, RUTE_SHIDS; | Q0T626, RUTE_SHIF8; |
| Q83RV4, RUTE_SHIFL; | Q3Z3A5, RUTE_SHISS; | A1JMW8, RUTE_YERE8; |
| Q8X505, YDFG_ECO57; | Q8FHD2, YDFG_ECOL6; | P39831, YDFG_ECOLI; |
| P69935, YDFG_SALTI; | P69936, YDFG_SALTY; | Q83RE8, YDFG_SHIFL; |
|
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