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ENZYME entry: EC 1.1.1.3
Accepted Name |
homoserine dehydrogenase.
|
Reaction catalysed |
- L-homoserine + NAD(+) <=> H(+) + L-aspartate 4-semialdehyde + NADH
- L-homoserine + NADP(+) <=> H(+) + L-aspartate 4-semialdehyde + NADPH
|
Comment(s) |
- The enzyme from Saccharomyces cerevisiae acts most rapidly with
NAD(+); the Neurospora enzyme with NADP(+).
- The enzyme from Escherichia coli is a multifunctional protein, which
also catalyzes the reaction of EC 2.7.2.4.
|
Cross-references |
BRENDA | 1.1.1.3 |
EC2PDB | 1.1.1.3 |
ExplorEnz | 1.1.1.3 |
PRIAM enzyme-specific profiles | 1.1.1.3 |
KEGG Ligand Database for Enzyme Nomenclature | 1.1.1.3 |
IUBMB Enzyme Nomenclature | 1.1.1.3 |
IntEnz | 1.1.1.3 |
MEDLINE | Find literature relating to 1.1.1.3 |
MetaCyc | 1.1.1.3 |
Rhea expert-curated reactions | 1.1.1.3 |
UniProtKB/Swiss-Prot |
P00561, AK1H_ECOLI; | P27725, AK1H_SERMA; | P00562, AK2H_ECOLI; |
Q9SA18, AKH1_ARATH; | P49079, AKH1_MAIZE; | O81852, AKH2_ARATH; |
P49080, AKH2_MAIZE; | P57290, AKH_BUCAI; | Q8K9U9, AKH_BUCAP; |
Q89AR4, AKH_BUCBP; | P37142, AKH_DAUCA; | P44505, AKH_HAEIN; |
P19582, DHOM_BACSU; | P08499, DHOM_CORGL; | Q5B998, DHOM_EMENI; |
Q9ZL20, DHOM_HELPJ; | P56429, DHOM_HELPY; | Q9CGD8, DHOM_LACLA; |
P52985, DHOM_LACLC; | P37143, DHOM_METGL; | Q58997, DHOM_METJA; |
P63630, DHOM_MYCBO; | P46806, DHOM_MYCLE; | P9WPX0, DHOM_MYCTO; |
P9WPX1, DHOM_MYCTU; | P29365, DHOM_PSEAE; | O94671, DHOM_SCHPO; |
P52986, DHOM_SYNY3; | P31116, DHOM_YEAST; | P37144, DHON_METGL; |
|
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All
ENZYME /
UniProtKB/Swiss-Prot entries corresponding to 1.1.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.1.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.-.-.-