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ENZYME

ENZYME entry: EC 2.7.2.4

Accepted Name
aspartate kinase
Alternative Name(s)
aspartokinase
Reaction catalysed
ATP + L-aspartate = 4-phospho-L-aspartate + ADP
Comment(s)
  • The enzyme from Escherichia coli is a multifunctional protein, which also catalyzes the reaction of EC 1.1.1.3.
  • This is also the case for two of the four isoenzymes in Arabidopsis thaliana.
  • The equilibrium constant strongly favors the reaction from right to left, i.e. the non-physiological direction of reaction.
Cross-references
BRENDA2.7.2.4
EC2PDB2.7.2.4
ExplorEnz2.7.2.4
PRIAM enzyme-specific profiles2.7.2.4
KEGG Ligand Database for Enzyme Nomenclature2.7.2.4
IUBMB Enzyme Nomenclature2.7.2.4
IntEnz2.7.2.4
MEDLINEFind literature relating to 2.7.2.4
MetaCyc2.7.2.4
Rhea expert-curated reactions2.7.2.4
UniProtKB/Swiss-Prot
P00561, AK1H_ECOLIP27725, AK1H_SERMAQ9LYU8, AK1_ARATH
Q04795, AK1_BACSUP00562, AK2H_ECOLIO23653, AK2_ARATH
P08495, AK2_BACSUQ9S702, AK3_ARATHP94417, AK3_BACSU
P08660, AK3_ECOLIA4VFY3, AKECT_STUS1Q9SA18, AKH1_ARATH
P49079, AKH1_MAIZEO81852, AKH2_ARATHP49080, AKH2_MAIZE
P57290, AKH_BUCAIQ8K9U9, AKH_BUCAPQ89AR4, AKH_BUCBP
P37142, AKH_DAUCAP44505, AKH_HAEINA4VJB4, AKLYS_STUS1
O67221, AK_AQUAEQ59229, AK_BACSGQ9PK32, AK_CHLMU
Q9Z6L0, AK_CHLPNO84367, AK_CHLTRQ8RQN1, AK_COREF
P41398, AK_CORFLP26512, AK_CORGLP53553, AK_GEOSE
Q9ZJZ7, AK_HELPJO25827, AK_HELPYQ57991, AK_METJA
P0A4Z9, AK_MYCBOP41403, AK_MYCSMP9WPX2, AK_MYCTO
P9WPX3, AK_MYCTUO69077, AK_PSEAEC3JXY0, AK_PSEFS
Q88EI9, AK_PSEPKQ1RGM9, AK_RICBRQ92GF9, AK_RICCN
Q4UK84, AK_RICFEQ9ZCI7, AK_RICPRQ68VZ7, AK_RICTY
O60163, AK_SCHPOP61488, AK_THET2P61489, AK_THETH
P10869, AK_YEASTA0A0D2YG09, FUB3_FUSO4S0DVT6, FUB3_GIBF5
W7MS01, FUB3_GIBM7

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.7.2.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.7.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.-.-.-