ENZYME entry: EC 1.1.1.363

Accepted Name
Glucose-6-phosphate dehydrogenase (NAD(P)(+)).
Alternative Name(s)
G6PD.
G6PDH.
Glc6PD.
Reaction catalysed
D-glucose 6-phosphate + NAD(P)(+) <=> 6-phospho-D-glucono-1,5-lactone + NAD(P)H
Comment(s)
  • The enzyme catalyzes a step of the pentose phosphate pathway.
  • The enzyme from the Gram-positive bacterium Leuconostoc mesenteroides prefers NADP(+) while the enzyme from the Gram-negative bacterium Gluconacetobacter xylinus prefers NAD(+).
  • Cf. EC 1.1.1.49 and EC 1.1.1.388.
Cross-references
BRENDA1.1.1.363
EC2PDB1.1.1.363
ExplorEnz1.1.1.363
PRIAM enzyme-specific profiles1.1.1.363
KEGG Ligand Database for Enzyme Nomenclature1.1.1.363
IUBMB Enzyme Nomenclature1.1.1.363
IntEnz1.1.1.363
MEDLINEFind literature relating to 1.1.1.363
MetaCyc1.1.1.363
UniProtKB/Swiss-Prot
P11411, G6PD_LEUME;  O68282, G6PD_PSEAE;  O95479, G6PE_HUMAN;  
Q8CFX1, G6PE_MOUSE;  P56201, G6PE_RABIT;  

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