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ENZYME entry: EC 1.1.1.382

Accepted Name
Ketol-acid reductoisomerase (NAD(+)).
Reaction catalysed
(2R)-2,3-dihydroxy-3-methylbutanoate + NAD(+) <=> (2S)-2-hydroxy-2-methyl-3-oxobutanoate + NADH
Comment(s)
The enzyme, characterized from the bacteria Thermacetogenium phaeum and Desulfococcus oleovorans and from the archaeon Archaeoglobus fulgidus, is specific for NADH (cf. EC 1.1.1.86 and EC 1.1.1.383).
Cross-references
BRENDA1.1.1.382
EC2PDB1.1.1.382
ExplorEnz1.1.1.382
PRIAM enzyme-specific profiles1.1.1.382
KEGG Ligand Database for Enzyme Nomenclature1.1.1.382
IUBMB Enzyme Nomenclature1.1.1.382
IntEnz1.1.1.382
MEDLINEFind literature relating to 1.1.1.382
MetaCyc1.1.1.382
Rhea expert-curated reactions1.1.1.382
UniProtKB/Swiss-Prot
A8ZTR0, ILVC_DESOH;  K4LVZ1, ILVC_THEPS;  Q64BR7, ILVC_UNCAG;  

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