Expasy logo

ENZYME

ENZYME entry: EC 1.1.1.392

Accepted Name
3alpha-hydroxycholanate dehydrogenase (NADP(+))
Alternative Name(s)
alpha-hydroxy-cholanate dehydrogenase
Reaction catalysed
lithocholate + NADP(+) <=> 3-oxo-5beta-cholan-24-oate + H(+) + NADPH
Comment(s)
  • This bacterial enzyme is involved in the modification of secondary bile acids to form 3beta-bile acids (also known as iso-bile acids) via a 3-oxo intermediate.
  • The enzyme catalyzes a reversible reaction in vitro.
  • Also acts on related bile acids. cf. EC 1.1.1.52.
Cross-references
BRENDA1.1.1.392
EC2PDB1.1.1.392
ExplorEnz1.1.1.392
PRIAM enzyme-specific profiles1.1.1.392
KEGG Ligand Database for Enzyme Nomenclature1.1.1.392
IUBMB Enzyme Nomenclature1.1.1.392
IntEnz1.1.1.392
MEDLINEFind literature relating to 1.1.1.392
MetaCyc1.1.1.392
Rhea expert-curated reactions1.1.1.392
UniProtKB/Swiss-Prot
A7B3K3, 3AHDP_RUMGV

View entry in original ENZYME format
View entry in raw text format (no links)
All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.1.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.1.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.-.-.-