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A new class EC 7, Translocases, has been added to the EC list. It will be part of ENZYME from release 2018_10. Read more about EC 7 here.

ENZYME entry: EC 1.1.1.52

Accepted Name
3-alpha-hydroxycholanate dehydrogenase (NAD(+)).
Reaction catalysed
Lithocholate + NAD(+) <=> 3-oxo-5-beta-cholan-24-oate + NADH
Comment(s)
  • Also acts on other 3-alpha-hydroxysteroids with an acidic side-chain.
  • Cf. EC 1.1.1.392.
Cross-references
BRENDA1.1.1.52
EC2PDB1.1.1.52
ExplorEnz1.1.1.52
PRIAM enzyme-specific profiles1.1.1.52
KEGG Ligand Database for Enzyme Nomenclature1.1.1.52
IUBMB Enzyme Nomenclature1.1.1.52
IntEnz1.1.1.52
MEDLINEFind literature relating to 1.1.1.52
MetaCyc1.1.1.52
UniProtKB/Swiss-Prot
C8WMP0, 3AHD_EGGLE

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.1.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.1.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.-.-.-