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ENZYME entry: EC 1.1.1.405

Accepted Name
ribitol-5-phosphate 2-dehydrogenase (NADP(+)).
Alternative Name(s)
D-ribulose 5-phosphate reductase.
ribulose-5-phosphate reductase.
ribulose-5-P reductase.
Reaction catalysed
D-ribitol 5-phosphate + NADP(+) <=> D-ribulose 5-phosphate + H(+) + NADPH
Comment(s)
  • The enzyme, characterized in bacteria, is specific for NADP.
  • It is part of the synthesis pathway of CDP-ribitol.
  • In Haemophilus influenzae it is part of a multifunctional enzyme also catalyzing EC 2.7.7.40.
  • Cf. EC 1.1.1.137.
Cross-references
BRENDA1.1.1.405
EC2PDB1.1.1.405
ExplorEnz1.1.1.405
PRIAM enzyme-specific profiles1.1.1.405
KEGG Ligand Database for Enzyme Nomenclature1.1.1.405
IUBMB Enzyme Nomenclature1.1.1.405
IntEnz1.1.1.405
MEDLINEFind literature relating to 1.1.1.405
MetaCyc1.1.1.405
Rhea expert-curated reactions1.1.1.405
UniProtKB/Swiss-Prot
Q48154, ACS1_HAEIF;  Q48230, BCS1_HAEIF;  Q2G1B9, TARJ1_STAA8;  
Q2G1C4, TARJ2_STAA8;  Q8RKJ0, TARJ_BACSH;  Q8DPI3, TARJ_STRR6;  

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