ENZYME entry: EC 1.1.1.413
| Accepted Name | ||
|---|---|---|
| A-factor type gamma-butyrolactone 1'-reductase (1S-forming) | ||
| Reaction catalysed | ||
| a (3R,4R)-3-[(1S)-1-hydroxyalkyl]-4-(hydroxymethyl)oxolan-2-one + NADP(+) = a (3R,4R)-3-alkanoyl-4-(hydroxymethyl)oxolan-2-one + NADPH + H(+) | ||
| Comment(s) | ||
| The enzyme, which is found in bacteria that produce virginiae- butanolide (VB) type gamma-butyrolactone autoregulators, reduces its substrate stereospecifically, forming a hydroxyl group in the (S) configuration. | ||
| Cross-references | ||
| BRENDA | 1.1.1.413 | |
| EC2PDB | 1.1.1.413 | |
| ExplorEnz | 1.1.1.413 | |
| KEGG Ligand Database for Enzyme Nomenclature | 1.1.1.413 | |
| IUBMB Enzyme Nomenclature | 1.1.1.413 | |
| MEDLINE | Find literature relating to 1.1.1.413 | |
| MetaCyc | 1.1.1.413 | |
| Rhea expert-curated reactions | 1.1.1.413 | |
| UniProtKB/Swiss-Prot |
| |
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