ENZYME entry: EC 1.1.1.413
Accepted Name |
A-factor type gamma-butyrolactone 1'-reductase (1S-forming).
|
Reaction catalysed |
A (3R,4R)-3-((1S)-1-hydroxyalkyl)-4-(hydroxymethyl)oxolan-2-one + NADP(+) <=> a (3R,4R)-3-alkanoyl-4-(hydroxymethyl)oxolan-2-one + NADPH |
Comment(s) |
The enzyme, which is found in bacteria that produce virginiae-
butanolide (VB) type gamma-butyrolactone autoregulators, reduces its
substrate stereospecifically, forming a hydroxyl group in the (S)
configuration.
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Cross-references |
BRENDA | 1.1.1.413 |
EC2PDB | 1.1.1.413 |
ExplorEnz | 1.1.1.413 |
PRIAM enzyme-specific profiles | 1.1.1.413 |
KEGG Ligand Database for Enzyme Nomenclature | 1.1.1.413 |
IUBMB Enzyme Nomenclature | 1.1.1.413 |
IntEnz | 1.1.1.413 |
MEDLINE | Find literature relating to 1.1.1.413 |
MetaCyc | 1.1.1.413 |
Rhea expert-curated reactions | 1.1.1.413 |
UniProtKB/Swiss-Prot |
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