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ENZYME entry: EC 1.1.1.418

Accepted Name
plant 3beta-hydroxysteroid-4alpha-carboxylate 3-dehydrogenase (decarboxylating).
Alternative Name(s)
3beta-hydroxysteroid dehydrogenases/C-4 decarboxylase.
Reaction catalysed
a 3beta-hydroxysteroid-4alpha-carboxylate + NAD(+) <=> a 3-oxosteroid + CO2 + NADH
Comment(s)
  • The enzyme, found in plants, catalyzes multiple reactions during plant sterol biosynthesis.
  • Unlike the fungal/animal enzyme EC 1.1.1.170 the plant enzyme is specific for NAD(+).
Cross-references
BRENDA1.1.1.418
EC2PDB1.1.1.418
ExplorEnz1.1.1.418
PRIAM enzyme-specific profiles1.1.1.418
KEGG Ligand Database for Enzyme Nomenclature1.1.1.418
IUBMB Enzyme Nomenclature1.1.1.418
IntEnz1.1.1.418
MEDLINEFind literature relating to 1.1.1.418
MetaCyc1.1.1.418
Rhea expert-curated reactions1.1.1.418
UniProtKB/Swiss-Prot
Q9FX01, HSDD1_ARATH;  Q67ZE1, HSDD2_ARATH;  

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