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ENZYME

ENZYME entry: EC 1.1.1.44

PURL: https://purl.expasy.org/enzyme/EC/1.1.1.44
Accepted Name
phosphogluconate dehydrogenase (NADP(+)-dependent, decarboxylating)
Alternative Name(s)
6PGD
6-phosphogluconic carboxylase
6-phosphogluconic dehydrogenase
phosphogluconic acid dehydrogenase
Reaction catalysed
6-phospho-D-gluconate + NADP(+) = D-ribulose 5-phosphate + CO2 + NADPH
Comment(s)
  • The enzyme participates in the oxidative branch of the pentose phosphate pathway, whose main purpose is to produce NADPH and pentose for biosynthetic reactions.
  • Highly specific for NADP(+). cf. EC 1.1.1.343.
Cross-references
BRENDA1.1.1.44
EC2PDB1.1.1.44
ExplorEnz1.1.1.44
KEGG Ligand Database for Enzyme Nomenclature1.1.1.44
IUBMB Enzyme Nomenclature1.1.1.44
MEDLINEFind literature relating to 1.1.1.44
MetaCyc1.1.1.44
Rhea expert-curated reactions1.1.1.44
UniProtKB/Swiss-Prot
Q9SH69, 6PGD1_ARATHQ9LI00, 6PGD1_ORYSJQ94KU1, 6PGD1_SPIOL
P38720, 6PGD1_YEASTQ9FWA3, 6PGD2_ARATHQ2R480, 6PGD2_ORYSJ
Q94KU2, 6PGD2_SPIOLP53319, 6PGD2_YEASTQ9FFR3, 6PGD3_ARATH
P37754, 6PGD9_ECOLXP70718, 6PGD_AGGACP52207, 6PGD_BACLI
P80859, 6PGD_BACSUP57208, 6PGD_BUCAIQ9ZHD9, 6PGD_BUCAP
Q89AX5, 6PGD_BUCBPQ17761, 6PGD_CAEELO13287, 6PGD_CANAX
P41570, 6PGD_CERCAQ9PKX7, 6PGD_CHLMUQ9Z8I3, 6PGD_CHLPN
O84066, 6PGD_CHLTRP41581, 6PGD_CITAMP41583, 6PGD_CITFR
P41582, 6PGD_CITKOO60037, 6PGD_CUNELQ8TA03, 6PGD_DICDI
P41572, 6PGD_DROMEP41573, 6PGD_DROSIP00350, 6PGD_ECOLI
C8VP36, 6PGD_EMENIQ7VMX4, 6PGD_HAEDUP43774, 6PGD_HAEIN
P52209, 6PGD_HUMANP41576, 6PGD_KLEPNQ9CHU6, 6PGD_LACLA
P96789, 6PGD_LACLMQ9DCD0, 6PGD_MOUSEP14332, 6PGD_PIG
P41574, 6PGD_PSEVUP41575, 6PGD_RAOPLP41577, 6PGD_RAOTE
P85968, 6PGD_RATP14062, 6PGD_SALTYP78812, 6PGD_SCHPO
P00349, 6PGD_SHEEPP41578, 6PGD_SHIBOP41579, 6PGD_SHIDY
P37756, 6PGD_SHIFLP41580, 6PGD_SHISOQ5HFR2, 6PGD_STAAC
Q931R3, 6PGD_STAAMP63334, 6PGD_STAANQ6GGI7, 6PGD_STAAR
Q6G954, 6PGD_STAASP63335, 6PGD_STAAWQ5HP42, 6PGD_STAEQ
Q8CP47, 6PGD_STAESP21577, 6PGD_SYNE7P52208, 6PGD_SYNY3
O83351, 6PGD_TREPAP31072, 6PGD_TRYBB

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.1.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.1.-.-
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