ENZYME entry: EC 1.1.1.343
Accepted Name |
phosphogluconate dehydrogenase (NAD(+)-dependent, decarboxylating).
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Alternative Name(s) |
6-PGDH. |
Reaction catalysed |
6-phospho-D-gluconate + NAD(+) <=> CO2 + D-ribulose 5-phosphate + NADH |
Comment(s) |
- Highly specific for NAD(+).
- The enzyme catalyzes both the oxidation and decarboxylation of
6-phospho-D-gluconate.
- In the bacterium Methylobacillus flagellatus the enzyme participates
in a formaldehyde oxidation pathway. cf. EC 1.1.1.44.
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Cross-references |
BRENDA | 1.1.1.343 |
EC2PDB | 1.1.1.343 |
ExplorEnz | 1.1.1.343 |
PRIAM enzyme-specific profiles | 1.1.1.343 |
KEGG Ligand Database for Enzyme Nomenclature | 1.1.1.343 |
IUBMB Enzyme Nomenclature | 1.1.1.343 |
IntEnz | 1.1.1.343 |
MEDLINE | Find literature relating to 1.1.1.343 |
MetaCyc | 1.1.1.343 |
Rhea expert-curated reactions | 1.1.1.343 |
UniProtKB/Swiss-Prot |
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