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ENZYME

ENZYME entry: EC 1.1.1.53

PURL: https://purl.expasy.org/enzyme/EC/1.1.1.53
Accepted Name
3alpha(or 20beta)-hydroxysteroid dehydrogenase
Alternative Name(s)
(R)-20-hydroxysteroid dehydrogenase
cortisone reductase
Reaction catalysed
androstan-3alpha,17beta-diol + NAD(+) = 17beta-hydroxyandrostanone + NADH + H(+)
Comment(s)
The 3alpha-hydroxy group or 20beta-hydroxy group of pregnane and androstane steroids can act as donor.
Cross-references
BRENDA1.1.1.53
EC2PDB1.1.1.53
ExplorEnz1.1.1.53
KEGG Ligand Database for Enzyme Nomenclature1.1.1.53
IUBMB Enzyme Nomenclature1.1.1.53
MEDLINEFind literature relating to 1.1.1.53
MetaCyc1.1.1.53
Rhea expert-curated reactions1.1.1.53
UniProtKB/Swiss-Prot
Q04828, AK1C1_HUMANQ95JH7, AK1C1_MACFAQ95JH6, AK1C1_MACFU
Q5REQ0, AK1C1_PONABP05980, AK1C3_BOVINP42330, AK1C3_HUMAN
Q5R7C9, AK1C3_PONABP52898, AK1C4_BOVINP17516, AK1C4_HUMAN
Q95JH5, AK1C4_MACFAQ95JH4, AK1C4_MACFUQ8HYR6, DHRS9_BOVIN
Q9BPW9, DHRS9_HUMANQ58NB6, DHRS9_MOUSEQ8VD48, DHRS9_RAT
Q3T001, H17B6_BOVINO14756, H17B6_HUMANQ9R092, H17B6_MOUSE
O54753, H17B6_RATO02691, HCD2_BOVINO18404, HCD2_DROME
Q99714, HCD2_HUMANO08756, HCD2_MOUSEO70351, HCD2_RAT
P69166, HSD_MYCBOP9WGT0, HSD_MYCTOP9WGT1, HSD_MYCTU
P19992, HSD_STREXO75452, RDH16_HUMANO54909, RDH16_MOUSE
P50170, RDH16_RATQ27979, RDH5_BOVINQ92781, RDH5_HUMAN
O55240, RDH5_MOUSE

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.1.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.1.-.-
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