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ENZYME

ENZYME entry: EC 1.1.99.39

Accepted Name
D-2-hydroxyglutarate dehydrogenase
Reaction catalysed
(R)-2-hydroxyglutarate + A <=> 2-oxoglutarate + AH2
Comment(s)
  • The enzyme has no activity with NAD(+) or NADP(+), and was assayed in vitro using artificial electron acceptors.
  • It has lower activity with (R)-lactate, (R)-2-hydroxybutyrate and meso-tartrate, and no activity with the (S) isomers.
Cross-references
BRENDA1.1.99.39
EC2PDB1.1.99.39
ExplorEnz1.1.99.39
PRIAM enzyme-specific profiles1.1.99.39
KEGG Ligand Database for Enzyme Nomenclature1.1.99.39
IUBMB Enzyme Nomenclature1.1.99.39
IntEnz1.1.99.39
MEDLINEFind literature relating to 1.1.99.39
MetaCyc1.1.99.39
Rhea expert-curated reactions1.1.99.39
UniProtKB/Swiss-Prot
O23240, D2HDH_ARATHQ1JPD3, D2HDH_BOVINA1L258, D2HDH_DANRE
P77748, D2HDH_ECOLIQ57252, D2HDH_HAEINQ8N465, D2HDH_HUMAN
Q8CIM3, D2HDH_MOUSEB8B7X6, D2HDH_ORYSIQ7XI14, D2HDH_ORYSJ
A0A0H3KZS3, D2HDH_PANAAA4VGK4, D2HDH_PSEU5P84850, D2HDH_RAT
P0DV35, D2HDH_XANCL

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