ENZYME entry: EC 1.1.99.39
Accepted Name |
D-2-hydroxyglutarate dehydrogenase.
|
Reaction catalysed |
(R)-2-hydroxyglutarate + acceptor <=> 2-oxoglutarate + reduced acceptor |
Cofactor(s) |
FAD.
|
Comment(s) |
- The enzyme has no activity with NAD(+) or NADP(+), and was assayed in
vitro using artificial electron acceptors.
- It has lower activity with (R)-lactate, (R)-2-hydroxybutyrate and
meso-tartrate, and no activity with the (S) isomers.
|
Cross-references |
BRENDA | 1.1.99.39 |
EC2PDB | 1.1.99.39 |
ExplorEnz | 1.1.99.39 |
PRIAM enzyme-specific profiles | 1.1.99.39 |
KEGG Ligand Database for Enzyme Nomenclature | 1.1.99.39 |
IUBMB Enzyme Nomenclature | 1.1.99.39 |
IntEnz | 1.1.99.39 |
MEDLINE | Find literature relating to 1.1.99.39 |
MetaCyc | 1.1.99.39 |
Rhea expert-curated reactions | 1.1.99.39 |
UniProtKB/Swiss-Prot |
O23240, D2HDH_ARATH; | Q1JPD3, D2HDH_BOVIN; | A1L258, D2HDH_DANRE; |
Q8N465, D2HDH_HUMAN; | Q8CIM3, D2HDH_MOUSE; | B8B7X6, D2HDH_ORYSI; |
Q7XI14, D2HDH_ORYSJ; | A4VGK4, D2HDH_PSEU5; | P84850, D2HDH_RAT; |
P0DV35, D2HDH_XANCL; |
|
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