A new class EC 7, Translocases, has been added to the EC list. It will be part of ENZYME from release 2018_10. Read more about EC 7 here.

ENZYME entry: EC 1.1.99.7

Accepted Name
Lactate--malate transhydrogenase.
Reaction catalysed
(S)-lactate + oxaloacetate <=> pyruvate + malate
Comment(s)
  • Catalyzes hydrogen transfer from C(3) or C(4) (S)-2-hydroxy acids to 2-oxo acids.
  • Contains tightly bound nicotinamide nucleotide in its active center.
  • This prosthetic group cannot be removed without denaturation of the protein.
Cross-references
BRENDA1.1.99.7
EC2PDB1.1.99.7
ExplorEnz1.1.99.7
PRIAM enzyme-specific profiles1.1.99.7
KEGG Ligand Database for Enzyme Nomenclature1.1.99.7
IUBMB Enzyme Nomenclature1.1.99.7
IntEnz1.1.99.7
MEDLINEFind literature relating to 1.1.99.7
MetaCyc1.1.99.7

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.1.99.-
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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.-.-.-