ENZYME entry: EC 1.11.1.12
Accepted Name |
Phospholipid-hydroperoxide glutathione peroxidase.
|
Alternative Name(s) |
Peroxidation-inhibiting protein. |
Reaction catalysed |
2 glutathione + a hydroperoxy-fatty-acyl-[lipid] <=> glutathione disulfide + a hydroxy-fatty-acyl-[lipid] + H(2)O |
Cofactor(s) |
Se(2+).
|
Comment(s) |
The products of action of EC 1.13.11.12 on phospholipids can act as
acceptor; H(2)O(2) can also act, but much more slowly (cf.
EC 1.11.1.9).
|
Cross-references |
PROSITE | PDOC00396 |
BRENDA | 1.11.1.12 |
EC2PDB | 1.11.1.12 |
ExplorEnz | 1.11.1.12 |
PRIAM enzyme-specific profiles | 1.11.1.12 |
KEGG Ligand Database for Enzyme Nomenclature | 1.11.1.12 |
IUBMB Enzyme Nomenclature | 1.11.1.12 |
IntEnz | 1.11.1.12 |
MEDLINE | Find literature relating to 1.11.1.12 |
MetaCyc | 1.11.1.12 |
Rhea expert-curated reactions | 1.11.1.12 |
UniProtKB/Swiss-Prot |
P52032, GPX1_ARATH; | O24296, GPX1_PEA; | Q9N2J2, GPX4_BOVIN; |
Q32QL6, GPX4_CALJA; | Q06652, GPX4_CITSI; | O49069, GPX4_GOSHI; |
O23968, GPX4_HELAN; | P36969, GPX4_HUMAN; | Q4AEH1, GPX4_HYLLA; |
Q4AEH0, GPX4_MACFU; | Q9LEF0, GPX4_MESCR; | O70325, GPX4_MOUSE; |
P30708, GPX4_NICSY; | P36968, GPX4_PIG; | Q4AEH2, GPX4_PONPY; |
P36970, GPX4_RAT; | Q4AEG9, GPX4_SAPAP; | O24031, GPX4_SOLLC; |
O23814, GPX4_SPIOL; | Q9FXS3, GPX4_TOBAC; | O48646, GPX6_ARATH; |
Q8SSH7, GPX_ENCCU; |
|
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ENZYME /
UniProtKB/Swiss-Prot entries corresponding to 1.11.1.-
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