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ENZYME entry: EC 1.13.11.12
Accepted Name |
linoleate 13S-lipoxygenase.
|
Alternative Name(s) |
13-lipoperoxidase. |
13-lipoxidase. |
carotene oxidase. |
lipoperoxidase. |
lipoxidase. |
Reaction catalysed |
- (9Z,12Z)-octadecadienoate + O2 <=> (13S)-hydroperoxy-(9Z,11E)-octadecadienoate
- (9Z,12Z,15Z)-octadecatrienoate + O2 <=> (13S)-hydroperoxy-(9Z,11E,15Z)-octadecatrienoate
|
Comment(s) |
- A common plant lipoxygenase that oxidizes linoleate and alpha-
linolenate, the two most common polyunsaturated fatty acids in
plants, by inserting molecular oxygen at the C13 position with (S)-
configuration.
- This enzyme produces precursors for several important compounds,
including the plant hormone jasmonic acid.
- EC 1.13.11.58 catalyzes a similar reaction at the second available
position of these fatty acids.
- Formerly EC 1.13.1.13 and EC 1.99.2.1.
|
Cross-references |
BRENDA | 1.13.11.12 |
EC2PDB | 1.13.11.12 |
ExplorEnz | 1.13.11.12 |
PRIAM enzyme-specific profiles | 1.13.11.12 |
KEGG Ligand Database for Enzyme Nomenclature | 1.13.11.12 |
IUBMB Enzyme Nomenclature | 1.13.11.12 |
IntEnz | 1.13.11.12 |
MEDLINE | Find literature relating to 1.13.11.12 |
MetaCyc | 1.13.11.12 |
Rhea expert-curated reactions | 1.13.11.12 |
UniProtKB/Swiss-Prot |
P27479, LOX15_BOVIN; | P16050, LOX15_HUMAN; | P39654, LOX15_MOUSE; |
P16469, LOX15_PIG; | Q5RBE8, LOX15_PONAB; | P12530, LOX15_RABIT; |
Q02759, LOX15_RAT; | P08170, LOX1_SOYBN; | P93184, LOX21_HORVU; |
O24370, LOX21_SOLTU; | Q8GSM3, LOX22_HORVU; | Q8GSM2, LOX23_HORVU; |
P38418, LOX2_ARATH; | O24371, LOX31_SOLTU; | Q9LNR3, LOX3_ARATH; |
Q9FNX8, LOX4_ARATH; | Q7XV13, LOX5_ORYSJ; | Q9CAG3, LOX6_ARATH; |
Q8H016, LOX6_ORYSJ; | P27480, LOXA_PHAVU; | P27481, LOXB_PHAVU; |
P38419, LOXC1_ORYSJ; | Q84YK8, LOXC2_ORYSJ; | Q8RNT4, LOX_PSEAI; |
M5EES5, MNLOX_PLESI; |
|
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ENZYME /
UniProtKB/Swiss-Prot entries corresponding to 1.13.11.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.13.-.-
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