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ENZYME

ENZYME entry: EC 1.11.1.19

Accepted Name
dye decolorizing peroxidase
Alternative Name(s)
DyP
DyP-type peroxidase
Reaction catalysed
2 H2O2 + Reactive Blue 5 = 2,2'-disulfonyl azobenzene + 3-[(4-amino-6-chloro-1,3,5-triazin-2-yl)amino]benzenesulfonate + 2 H(+) + 2 H2O + phthalate
Comment(s)
  • Heme proteins with proximal histidine secreted by basidiomycetous fungi and eubacteria.
  • They are similar to EC 1.11.1.16 versatile peroxidase (oxidation of Reactive Black 5, phenols, veratryl alcohol), but differ from the latter in their ability to efficiently oxidize a number of recalcitrant anthraquinone dyes, and inability to oxidize Mn(II).
  • The model substrate Reactive Blue 5 is converted with high efficiency via a so far unique mechanism that combines oxidative and hydrolytic steps and leads to the formation of phthalic acid.
  • Bacterial TfuDyP catalyzes sulfoxidation.
Cross-references
BRENDA1.11.1.19
EC2PDB1.11.1.19
ExplorEnz1.11.1.19
PRIAM enzyme-specific profiles1.11.1.19
KEGG Ligand Database for Enzyme Nomenclature1.11.1.19
IUBMB Enzyme Nomenclature1.11.1.19
IntEnz1.11.1.19
MEDLINEFind literature relating to 1.11.1.19
MetaCyc1.11.1.19
Rhea expert-curated reactions1.11.1.19
UniProtKB/Swiss-Prot
K7N5M8, DYP2_AMYS7I2DBY1, DYP_AURAJI2DBY2, DYP_EXIGL
I2DBY3, DYP_MYCEPQ47KB1, DYP_THEFYB0BK71, MSP1_MYCSO

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