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ENZYME entry: EC 1.12.1.4

Accepted Name
Hydrogenase (NAD(+), ferredoxin).
Alternative Name(s)
Bifurcating (FeFe) hydrogenase.
Reaction catalysed
2 H(2) + NAD(+) + 2 oxidized ferredoxin <=> 5 H(+) + NADH + 2 reduced ferredoxin
Comment(s)
  • The enzyme from Thermotoga maritima contains a (FeFe) cluster (H-cluster) and iron-sulfur clusters.
  • It works in the direction evolving hydrogen as a means of eliminating excess reducing equivalents.
Cross-references
BRENDA1.12.1.4
EC2PDB1.12.1.4
ExplorEnz1.12.1.4
PRIAM enzyme-specific profiles1.12.1.4
KEGG Ligand Database for Enzyme Nomenclature1.12.1.4
IUBMB Enzyme Nomenclature1.12.1.4
IntEnz1.12.1.4
MEDLINEFind literature relating to 1.12.1.4
MetaCyc1.12.1.4
Rhea expert-curated reactions1.12.1.4

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.12.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.12.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.-.-.-