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ENZYME entry: EC 1.13.11.58

Accepted Name
linoleate 9S-lipoxygenase.
Alternative Name(s)
9-lipoxygenase.
9S-lipoxygenase.
linoleate 9-lipoxygenase.
Reaction catalysed
(9Z,12Z)-octadecadienoate + O2 <=> (9S)-hydroperoxy-(10E,12Z)-octadecadienoate
Comment(s)
  • A common plant lipoxygenase that oxidizes linoleate and alpha- linolenate, the two most common polyunsaturated fatty acids in plants, by inserting molecular oxygen at the C9 position with (S)- configuration.
  • The enzyme plays a physiological role during the early stages of seedling growth.
  • The enzyme from Arabidopsis thaliana shows comparable activity toward linoleate and linolenate.
  • EC 1.13.11.12 catalyzes a similar reaction at another position of these fatty acids.
Cross-references
BRENDA1.13.11.58
EC2PDB1.13.11.58
ExplorEnz1.13.11.58
PRIAM enzyme-specific profiles1.13.11.58
KEGG Ligand Database for Enzyme Nomenclature1.13.11.58
IUBMB Enzyme Nomenclature1.13.11.58
IntEnz1.13.11.58
MEDLINEFind literature relating to 1.13.11.58
MetaCyc1.13.11.58
Rhea expert-curated reactions1.13.11.58
UniProtKB/Swiss-Prot
O35936, ALOX8_MOUSE;  P37831, LOX11_SOLTU;  O24379, LOX12_SOLTU;  
Q43189, LOX13_SOLTU;  Q43190, LOX14_SOLTU;  Q43191, LOX15_SOLTU;  
Q41238, LOX16_SOLTU;  O22507, LOX17_SOLTU;  O22508, LOX18_SOLTU;  
Q06327, LOX1_ARATH;  P29114, LOX1_HORVU;  P38414, LOX1_LENCU;  
Q76I22, LOX1_ORYSJ;  P29250, LOX2_ORYSJ;  P14856, LOX2_PEA;  
P09439, LOX2_SOYBN;  Q7G794, LOX3_ORYSJ;  P09918, LOX3_PEA;  
P09186, LOX3_SOYBN;  Q53RB0, LOX4_ORYSJ;  P38417, LOX4_SOYBN;  
Q9LUW0, LOX5_ARATH;  P27480, LOXA_PHAVU;  P38415, LOXA_SOLLC;  
P27481, LOXB_PHAVU;  P38416, LOXB_SOLLC;  P24095, LOXX_SOYBN;  
Q8RNT4, LOX_PSEAI;  T0JRM4, MNLOX_COLGC;  G4NAP4, MNLOX_MAGO7;  
P0CT92, MNLOX_NAKOS;  

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