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ENZYME

ENZYME entry: EC 1.13.11.76

PURL: https://purl.expasy.org/enzyme/EC/1.13.11.76
Accepted Name
2-amino-5-chlorophenol 1,6-dioxygenase
Reaction catalysed
2-amino-5-chlorophenol + O2 = 2-amino-5-chloromuconate 6-semialdehyde
Comment(s)
  • The enzyme, a member of the nonheme-iron(II)-dependent dioxygenase family, is an extradiol-type dioxygenase that utilizes a non-heme ferrous iron to cleave the aromatic ring at the meta position (relative to the hydroxyl substituent).
  • The enzyme from the bacterium Comamonas testosteroni CNB-1 also has the activity of EC 1.3.1.74.
Cross-references
BRENDA1.13.11.76
EC2PDB1.13.11.76
ExplorEnz1.13.11.76
KEGG Ligand Database for Enzyme Nomenclature1.13.11.76
IUBMB Enzyme Nomenclature1.13.11.76
MEDLINEFind literature relating to 1.13.11.76
MetaCyc1.13.11.76
Rhea expert-curated reactions1.13.11.76
UniProtKB/Swiss-Prot
Q6J1Z6, AMNB_COMTE

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