ENZYME entry: EC 1.3.1.74
Accepted Name |
2-alkenal reductase (NAD(P)(+)).
|
Alternative Name(s) |
2-alkenal reductase. |
NAD(P)H-dependent alkenal/one oxidoreductase. |
NADPH:2-alkenal alpha,beta-hydrogenase. |
Reaction catalysed |
A n-alkanal + NAD(P)(+) <=> an alk-2-enal + NAD(P)H |
Comment(s) |
- Highly specific for 4-hydroxynon-2-enal and non-2-enal.
- Alk-2-enals of shorter chain have lower affinities.
- Exhibits high activities also for alk-2-enones such as but-3-en-2-one
and pent-3-en-2-one.
- Inactive with cyclohex-2-en-1-one and 12-oxophytodienoic acid.
- Involved in the detoxification of alpha,beta-unsaturated aldehydes
and ketones (cf. EC 1.3.1.102).
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Cross-references |
BRENDA | 1.3.1.74 |
EC2PDB | 1.3.1.74 |
ExplorEnz | 1.3.1.74 |
PRIAM enzyme-specific profiles | 1.3.1.74 |
KEGG Ligand Database for Enzyme Nomenclature | 1.3.1.74 |
IUBMB Enzyme Nomenclature | 1.3.1.74 |
IntEnz | 1.3.1.74 |
MEDLINE | Find literature relating to 1.3.1.74 |
MetaCyc | 1.3.1.74 |
Rhea expert-curated reactions | 1.3.1.74 |
UniProtKB/Swiss-Prot |
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