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A new class EC 7, Translocases, has been added to the EC list. It will be part of ENZYME from release 2018_10. Read more about EC 7 here.

ENZYME entry: EC

Accepted Name
2-alkenal reductase (NAD(P)(+)).
Alternative Name(s)
2-alkenal reductase.
NAD(P)H-dependent alkenal/one oxidoreductase.
NADPH:2-alkenal alpha,beta-hydrogenase.
Reaction catalysed
A n-alkanal + NAD(P)(+) <=> an alk-2-enal + NAD(P)H
  • Highly specific for 4-hydroxynon-2-enal and non-2-enal.
  • Alk-2-enals of shorter chain have lower affinities.
  • Exhibits high activities also for alk-2-enones such as but-3-en-2-one and pent-3-en-2-one.
  • Inactive with cyclohex-2-en-1-one and 12-oxophytodienoic acid.
  • Involved in the detoxification of alpha,beta-unsaturated aldehydes and ketones (cf. EC
PRIAM enzyme-specific profiles1.3.1.74
KEGG Ligand Database for Enzyme Nomenclature1.3.1.74
IUBMB Enzyme Nomenclature1.3.1.74
MEDLINEFind literature relating to
Q39172, AER_ARATH;  Q39173, P2_ARATH;  Q3SZJ4, PTGR1_BOVIN;  
Q29073, PTGR1_PIG;  Q28719, PTGR1_RABIT;  P97584, PTGR1_RAT;  

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All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.3.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.3.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.-.-.-