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ENZYME entry: EC 1.14.11.9
| Accepted Name |
|---|
| flavanone 3-dioxygenase.
|
| Alternative Name(s) |
|---|
| (2S)-flavanone 3-hydroxylase. |
| flavanone 3beta-hydroxylase. |
| flavanone 3-hydroxylase. |
| flavanone synthase I. |
| naringenin 3-dioxygenase. |
| naringenin 3-hydroxylase. |
| Reaction catalysed |
|---|
| 2-oxoglutarate + a (2S)-flavan-4-one + O2 <=> a (2R,3R)-dihydroflavonol + CO2 + succinate |
| Comment(s) |
|---|
- This plant enzyme catalyzes an early step in the flavonoid
biosynthesis pathway, leading to the production of flavanols and
anthocyanins.
- Substrates include (2S)-naringenin, (2S)-eriodictyol, (2S)-
dihydrotricetin and (2S)-pinocembrin.
- Some enzymes are bifuctional and also catalyze EC 1.14.20.6.
|
| Cross-references |
|---|
| BRENDA | 1.14.11.9 |
| EC2PDB | 1.14.11.9 |
| ExplorEnz | 1.14.11.9 |
| PRIAM enzyme-specific profiles | 1.14.11.9 |
| KEGG Ligand Database for Enzyme Nomenclature | 1.14.11.9 |
| IUBMB Enzyme Nomenclature | 1.14.11.9 |
| IntEnz | 1.14.11.9 |
| MEDLINE | Find literature relating to 1.14.11.9 |
| MetaCyc | 1.14.11.9 |
| Rhea expert-curated reactions | 1.14.11.9 |
| UniProtKB/Swiss-Prot |
| A0A4D6Q9B0, FL3H1_CROXC; | Q7XM21, FL3H1_ORYSJ; | A0A4D6Q4T7, FL3H2_CROXC; |
| Q8W2X5, FL3H2_ORYSJ; | Q7XR84, FL3H3_ORYSJ; | Q9S818, FL3H_ARATH; |
| Q05963, FL3H_CALCH; | Q05964, FL3H_DIACA; | P28038, FL3H_HORVU; |
| Q06942, FL3H_MALDO; | Q05965, FL3H_MATIN; | Q7XZQ7, FL3H_PETCR; |
| Q07353, FL3H_PETHY; | P41090, FL3H_VITVI; | Q96330, FLS1_ARATH; |
| Q9ZWQ9, FLS_CITUN; | Q9M547, FLS_EUSER; | Q9XHG2, FLS_MALDO; |
| O04395, FLS_MATIN; | Q7XZQ6, FLS_PETCR; | Q07512, FLS_PETHY; |
| Q41452, FLS_SOLTU; |
|
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ENZYME /
UniProtKB/Swiss-Prot entries corresponding to 1.14.11.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.14.-.-
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