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ENZYME

ENZYME entry: EC 1.14.13.113

Accepted Name
FAD-dependent urate hydroxylase
Alternative Name(s)
FAD-dependent urate oxidase
urate hydroxylase
Reaction catalysed
H(+) + NADH + O2 + urate = 5-hydroxyisourate + H2O + NAD(+)
Comment(s)
  • The reaction is part of the purine catabolic pathway in the bacterium Klebsiella pneumoniae.
  • The enzyme is different from EC 1.7.3.3, found in most plants, which produces hydrogen peroxide.
  • The product of the enzyme is a substrate for EC 3.5.2.17.
Cross-references
BRENDA1.14.13.113
EC2PDB1.14.13.113
ExplorEnz1.14.13.113
PRIAM enzyme-specific profiles1.14.13.113
KEGG Ligand Database for Enzyme Nomenclature1.14.13.113
IUBMB Enzyme Nomenclature1.14.13.113
IntEnz1.14.13.113
MEDLINEFind literature relating to 1.14.13.113
MetaCyc1.14.13.113
Rhea expert-curated reactions1.14.13.113
UniProtKB/Swiss-Prot
Q6F6Y2, HPXO_ACIADB5B0J6, HPXO_KLEOXA6T923, HPXO_KLEP7
B6D1N4, HPXO_KLEPNA1TFU9, HPXO_MYCVPQ8PDQ6, HPYO_XANCP

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