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ENZYME entry: EC 1.14.13.211

Accepted Name
Rifampicin monooxygenase.
Alternative Name(s)
RIF-O.
Reaction catalysed
Rifampicin + NAD(P)H + O(2) <=> 2'-N-hydroxyrifampicin + NAD(P)(+) + H(2)O
Comment(s)
  • The enzyme has been found in the Corynebacteria Rhodococcus equi and Nocardia farcinica.
  • It confers increased resistance to the antibiotic rifampicin by initiating its degradation.
Cross-references
BRENDA1.14.13.211
EC2PDB1.14.13.211
ExplorEnz1.14.13.211
PRIAM enzyme-specific profiles1.14.13.211
KEGG Ligand Database for Enzyme Nomenclature1.14.13.211
IUBMB Enzyme Nomenclature1.14.13.211
IntEnz1.14.13.211
MEDLINEFind literature relating to 1.14.13.211
MetaCyc1.14.13.211
Rhea expert-curated reactions1.14.13.211

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.14.13.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.14.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.-.-.-