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ENZYME entry: EC 1.14.13.232
| Accepted Name |
|---|
| 6-methylpretetramide 4-monooxygenase.
|
| Reaction catalysed |
|---|
| 6-methylpretetramide + 2 H(+) + NADPH + O2 <=> 4-hydroxy-6-methylpretetramide + H2O + NADP(+) |
| Comment(s) |
|---|
- The enzyme, characterized from the bacterium Streptomyces rimosus,
participates in the biosynthesis of tetracycline antibiotics.
- That bacterium possesses two enzymes that can catalyze the reaction -
OxyE is the main isozyme, while OxyL has a lower activity.
- OxyL is bifunctional, and its main function is EC 1.14.13.233.
|
| Cross-references |
|---|
| BRENDA | 1.14.13.232 |
| EC2PDB | 1.14.13.232 |
| ExplorEnz | 1.14.13.232 |
| PRIAM enzyme-specific profiles | 1.14.13.232 |
| KEGG Ligand Database for Enzyme Nomenclature | 1.14.13.232 |
| IUBMB Enzyme Nomenclature | 1.14.13.232 |
| IntEnz | 1.14.13.232 |
| MEDLINE | Find literature relating to 1.14.13.232 |
| MetaCyc | 1.14.13.232 |
| Rhea expert-curated reactions | 1.14.13.232 |
| UniProtKB/Swiss-Prot |
|
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