Home  |  Contact

ENZYME entry: EC 1.14.13.232

Accepted Name
6-methylpretetramide 4-monooxygenase.
Reaction catalysed
6-methylpretetramide + NADPH + O(2) <=> 4-hydroxy-6-methylpretetramide + NADP(+) + H(2)O
Cofactor(s)
FAD.
Comment(s)
  • The enzyme, characterized from the bacterium Streptomyces rimosus, participates in the biosynthesis of tetracycline antibiotics.
  • That bacterium possesses two enzymes that can catalyze the reaction - OxyE is the main isozyme, while OxyL has a lower activity.
  • OxyL is bifunctional, and its main function is EC 1.14.13.233.
Cross-references
BRENDA1.14.13.232
EC2PDB1.14.13.232
ExplorEnz1.14.13.232
PRIAM enzyme-specific profiles1.14.13.232
KEGG Ligand Database for Enzyme Nomenclature1.14.13.232
IUBMB Enzyme Nomenclature1.14.13.232
IntEnz1.14.13.232
MEDLINEFind literature relating to 1.14.13.232
MetaCyc1.14.13.232
UniProtKB/Swiss-Prot
Q3S8R0, OXYE_STRRM;  Q3S8Q4, OXYL_STRRM;  

View entry in original ENZYME format
View entry in raw text format (no links)
All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.14.13.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.14.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.-.-.-