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ENZYME entry: EC 1.14.13.232
Accepted Name |
6-methylpretetramide 4-monooxygenase.
|
Reaction catalysed |
6-methylpretetramide + 2 H(+) + NADPH + O2 <=> 4-hydroxy-6-methylpretetramide + H2O + NADP(+) |
Comment(s) |
- The enzyme, characterized from the bacterium Streptomyces rimosus,
participates in the biosynthesis of tetracycline antibiotics.
- That bacterium possesses two enzymes that can catalyze the reaction -
OxyE is the main isozyme, while OxyL has a lower activity.
- OxyL is bifunctional, and its main function is EC 1.14.13.233.
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Cross-references |
BRENDA | 1.14.13.232 |
EC2PDB | 1.14.13.232 |
ExplorEnz | 1.14.13.232 |
PRIAM enzyme-specific profiles | 1.14.13.232 |
KEGG Ligand Database for Enzyme Nomenclature | 1.14.13.232 |
IUBMB Enzyme Nomenclature | 1.14.13.232 |
IntEnz | 1.14.13.232 |
MEDLINE | Find literature relating to 1.14.13.232 |
MetaCyc | 1.14.13.232 |
Rhea expert-curated reactions | 1.14.13.232 |
UniProtKB/Swiss-Prot |
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ENZYME /
UniProtKB/Swiss-Prot entries corresponding to 1.14.13.-
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