ENZYME entry: EC 1.14.13.247
Accepted Name |
stachydrine N-demethylase.
|
Alternative Name(s) |
L-proline betaine N-demethylase. |
Reaction catalysed |
- H(+) + L-proline betaine + NADPH + O2 <=> formaldehyde + H2O + N-methyl-L-proline + NADP(+)
- H(+) + L-proline betaine + NADH + O2 <=> formaldehyde + H2O + N-methyl-L-proline + NAD(+)
|
Comment(s) |
- The enzyme, characterized from the bacterium Sinorhizobium meliloti
1021, consists of three different types of subunits.
- The catalytic unit contains a Rieske [2Fe-2S] iron-sulfur cluster,
and catalyzes the monooxygenation of a methyl group.
- The resulting N-methoxyl group is unstable and decomposes
spontaneously to form formaldehyde.
- The other subunits are involved in the transfer of electrons from
NAD(P)H to the catalytic subunit.
|
Cross-references |
BRENDA | 1.14.13.247 |
EC2PDB | 1.14.13.247 |
ExplorEnz | 1.14.13.247 |
PRIAM enzyme-specific profiles | 1.14.13.247 |
KEGG Ligand Database for Enzyme Nomenclature | 1.14.13.247 |
IUBMB Enzyme Nomenclature | 1.14.13.247 |
IntEnz | 1.14.13.247 |
MEDLINE | Find literature relating to 1.14.13.247 |
MetaCyc | 1.14.13.247 |
Rhea expert-curated reactions | 1.14.13.247 |
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ENZYME /
UniProtKB/Swiss-Prot entries corresponding to 1.14.13.-
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