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ENZYME entry: EC 1.14.13.32

Accepted Name
albendazole monooxygenase.
Alternative Name(s)
albendazole monooxygenase (flavin-containing).
albendazole sulfoxidase.
Reaction catalysed
albendazole + H(+) + NADPH + O2 <=> albendazole S-oxide + H2O + NADP(+)
Comment(s)
  • A microsomal flavin-containing monooxygenase.
  • A similar conversion is also carried out by some microsomal cytochrome P450 enzymes (EC 1.14.14.73).
  • It is estimated that cytochrome P450s are responsible for 70% of the activity.
Cross-references
BRENDA1.14.13.32
EC2PDB1.14.13.32
ExplorEnz1.14.13.32
PRIAM enzyme-specific profiles1.14.13.32
KEGG Ligand Database for Enzyme Nomenclature1.14.13.32
IUBMB Enzyme Nomenclature1.14.13.32
IntEnz1.14.13.32
MEDLINEFind literature relating to 1.14.13.32
MetaCyc1.14.13.32
Rhea expert-curated reactions1.14.13.32
UniProtKB/Swiss-Prot
Q8HYJ9, FMO3_BOVIN;  Q95LA1, FMO3_CANLF;  P49328, FMO3_CAVPO;  
P31513, FMO3_HUMAN;  Q8SPQ7, FMO3_MACMU;  P97501, FMO3_MOUSE;  
Q7YS44, FMO3_PANTR;  P32417, FMO3_RABIT;  Q9EQ76, FMO3_RAT;  

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