ENZYME entry: EC 1.14.13.84
Accepted Name |
4-hydroxyacetophenone monooxygenase.
|
Alternative Name(s) |
HAPMO. |
Reaction catalysed |
(4-hydroxyphenyl)ethan-1-one + NADPH + O(2) <=> 4-hydroxyphenyl acetate + NADP(+) + H(2)O |
Cofactor(s) |
FAD.
|
Comment(s) |
- The enzyme from Pseudomonas fluorescens ACB catalyzes the conversion
of a wide range of acetophenone derivatives.
- Highest activity occurs with compounds bearing an electron-donating
substituent at the para position of the aromatic ring.
- In the absence of substrate, the enzyme can act as an NADPH oxidase
(EC 1.6.3.1).
|
Cross-references |
BRENDA | 1.14.13.84 |
EC2PDB | 1.14.13.84 |
ExplorEnz | 1.14.13.84 |
PRIAM enzyme-specific profiles | 1.14.13.84 |
KEGG Ligand Database for Enzyme Nomenclature | 1.14.13.84 |
IUBMB Enzyme Nomenclature | 1.14.13.84 |
IntEnz | 1.14.13.84 |
MEDLINE | Find literature relating to 1.14.13.84 |
MetaCyc | 1.14.13.84 |
UniProtKB/Swiss-Prot |
|
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