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ENZYME

ENZYME entry: EC 1.14.13.84

PURL: https://purl.expasy.org/enzyme/EC/1.14.13.84
Accepted Name
4-hydroxyacetophenone monooxygenase
Alternative Name(s)
HAPMO
Reaction catalysed
4'-hydroxyacetophenone + NADPH + O2 + H(+) = 4-acetoxyphenol + NADP(+) + H2O
Comment(s)
  • The enzyme from Pseudomonas fluorescens ACB catalyzes the conversion of a wide range of acetophenone derivatives.
  • Highest activity occurs with compounds bearing an electron-donating substituent at the para position of the aromatic ring.
  • In the absence of substrate, the enzyme can act as an NADPH oxidase (EC 1.6.3.1).
Cross-references
BRENDA1.14.13.84
EC2PDB1.14.13.84
ExplorEnz1.14.13.84
KEGG Ligand Database for Enzyme Nomenclature1.14.13.84
IUBMB Enzyme Nomenclature1.14.13.84
MEDLINEFind literature relating to 1.14.13.84
MetaCyc1.14.13.84
Rhea expert-curated reactions1.14.13.84
UniProtKB/Swiss-Prot
Q93TJ5, HAPMO_PSEFL

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