ENZYME entry: EC 1.14.14.13
Accepted Name |
4-(gamma-L-glutamylamino)butanoyl-[BtrI acyl-carrier protein]
monooxygenase.
|
Reaction catalysed |
4-(gamma-L-glutamylamino)butanoy-[BtrI ACP] + FMNH2 + O2 <=> 4-(gamma-L-glutamylamino)-(2S)-2-hydroxybutanoyl-[BtrI ACP] + FMN + H(+) + H2O |
Comment(s) |
- Catalyzes a step in the biosynthesis of the side chain of the
aminoglycoside antibiotics of the butirosin family.
- Forms a complex with a dedicated NAD(P)H:FMN oxidoreductase.
- The enzyme is not able to hydroxylate free substrates, activation by
the acyl-carrier protein is mandatory.
- Octanoyl-S-[BtrI acyl-carrier protein] is also accepted.
|
Cross-references |
BRENDA | 1.14.14.13 |
EC2PDB | 1.14.14.13 |
ExplorEnz | 1.14.14.13 |
PRIAM enzyme-specific profiles | 1.14.14.13 |
KEGG Ligand Database for Enzyme Nomenclature | 1.14.14.13 |
IUBMB Enzyme Nomenclature | 1.14.14.13 |
IntEnz | 1.14.14.13 |
MEDLINE | Find literature relating to 1.14.14.13 |
MetaCyc | 1.14.14.13 |
Rhea expert-curated reactions | 1.14.14.13 |
UniProtKB/Swiss-Prot |
|
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