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ENZYME entry: EC 1.14.14.142

Accepted Name
8-dimethylallylnaringenin 2'-hydroxylase.
Alternative Name(s)
8-DMAN 2'-hydroxylase.
Reaction catalysed
Sophoraflavanone B + [reduced NADPH--hemoprotein reductase] + O(2) <=> leachianone G + [oxidized NADPH--hemoprotein reductase] + H(2)O
Cofactor(s)
Heme-thiolate.
Comment(s)
  • A membrane-bound cytochrome P450 (heme-thiolate) protein that is associated with the endoplasmic reticulum.
  • This enzyme is specific for sophoraflavanone B as substrate.
  • Along with EC 2.5.1.70 and EC 2.5.1.71, this enzyme forms part of the sophoraflavanone G biosynthetic pathway.
  • Formerly EC 1.14.13.103.
Cross-references
BRENDA1.14.14.142
EC2PDB1.14.14.142
ExplorEnz1.14.14.142
PRIAM enzyme-specific profiles1.14.14.142
KEGG Ligand Database for Enzyme Nomenclature1.14.14.142
IUBMB Enzyme Nomenclature1.14.14.142
IntEnz1.14.14.142
MEDLINEFind literature relating to 1.14.14.142
MetaCyc1.14.14.142
Rhea expert-curated reactions1.14.14.142

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.14.14.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.14.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.-.-.-