ENZYME

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A new class EC 7, Translocases, has been added to the EC list. It will be part of ENZYME from release 2018_10. Read more about EC 7 here.

ENZYME entry: EC 2.5.1.71

Accepted Name
Leachianone-G 2''-dimethylallyltransferase.
Alternative Name(s)
Leachianone G 2''-dimethylallyltransferase.
LG 2''-dimethylallyltransferase.
LGDT.
Reaction catalysed
Dimethylallyl diphosphate + leachianone G <=> diphosphate + sophoraflavanone G
Comment(s)
The reaction forms the lavandulyl sidechain of sophoraflavanone G by transferring a dimethylallyl group to the 2'' position of another dimethylallyl group attached at postiion 8 of leachianone G. The enzyme is specific for dimethylallyl diphosphate as the prenyl donor, as it cannot be replaced by isopentenyl diphosphate or geranyl diphosphate. Euchrenone a(7) (a 5-deoxy derivative of leachianone G) and kenusanone I (a 7-methoxy derivative of leachianone G) can also act as substrates, but more slowly. Along with EC 1.14.13.103 and EC 2.5.1.70, this enzyme forms part of the sophoraflavanone-G biosynthesis pathway.
Cross-references
BRENDA	2.5.1.71
EC2PDB	2.5.1.71
ExplorEnz	2.5.1.71
PRIAM enzyme-specific profiles	2.5.1.71
KEGG Ligand Database for Enzyme Nomenclature	2.5.1.71
IUBMB Enzyme Nomenclature	2.5.1.71
IntEnz	2.5.1.71
MEDLINE	Find literature relating to 2.5.1.71
MetaCyc	2.5.1.71