ENZYME entry: EC 1.14.14.179
| Accepted Name |
|---|
| brassinosteroid 6-oxygenase.
|
| Alternative Name(s) |
|---|
| brassinosteroid 6-oxidase. |
| CYP85A1. |
| CYP85A2. |
| Reaction catalysed |
|---|
| 6-deoxocastasterone + 2 O2 + 2 reduced [NADPH--hemoprotein reductase] <=> castasterone + 2 H(+) + 3 H2O + 2 oxidized [NADPH--hemoprotein reductase] |
| Comment(s) |
|---|
- This cytochrome P450 (heme thiolate) plant enzyme catalyzes the C-6
hydoxylation of several brassinosteroid biosynthesis intermediates,
and the further oxidation of the hydroxyl group to an oxo group.
- Substrates include 6-deoxocastasterone, 6-deoxotyphasterol,
3-dehydro-6-deoxoteasterone, and 6-deoxoteasterone.
- The CYP85A2 isozyme of Arabidopsis thaliana (but not the CYP85A1
isozyme) also catalyzes the activity of EC 1.14.14.180.
|
| Cross-references |
|---|
| BRENDA | 1.14.14.179 |
| EC2PDB | 1.14.14.179 |
| ExplorEnz | 1.14.14.179 |
| PRIAM enzyme-specific profiles | 1.14.14.179 |
| KEGG Ligand Database for Enzyme Nomenclature | 1.14.14.179 |
| IUBMB Enzyme Nomenclature | 1.14.14.179 |
| IntEnz | 1.14.14.179 |
| MEDLINE | Find literature relating to 1.14.14.179 |
| MetaCyc | 1.14.14.179 |
| Rhea expert-curated reactions | 1.14.14.179 |
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